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An investigation in adults to determine if physiological responses to visual food cues are associated with addictive eating behaviour

Physiological measures as novel biomarkers of addictive eating behaviours: a pilot study in adults to determine if physiological responses to visual food cues are associated with addictive eating behaviour

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619000410156
Enrollment
42
Registered
2019-03-13
Start date
2019-03-18
Completion date
2019-10-01
Last updated
2020-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This project is a pilot study in adults to investigate physiological measures as novel biomarkers of food addiction. Impaired physiological responses (e.g. heart rate variability, pupillary responses) have been found in other forms of dysfunctional eating patterns (e.g. binge eating, bulimia nervosa, obesity) and are linked to abnormal functioning of neural circulatory. This project will recruit males and females >18yrs to determine if physiological measures in response to visual food stimuli are associated with food addiction. It is hypothesised that adults presenting with moderate-severe food addiction symptom scores will have lower heart rate variability, increased sweat responses and greater attentional biases toward hyperpalatable foods (i.e. junk foods) compared to adults with low symptom scores.

Interventions

This pilot study has a within subject study design. After determining eligibility, via an online screening, participants will complete a series of standardised questionnaires (Yale Food Addiction Scale, Addiction-like Eating Behaviour Scale, The Self-Report Habit Index, The Power of Food Scale, Perceived Stress Scale, Generalized Anxiety Disorder scale, The Patient Health Questionnaire, The Substance Use Risk Profile Scale) online prior to attending a one-off experimental session at the Universi

This pilot study has a within subject study design. After determining eligibility, via an online screening, participants will complete a series of standardised questionnaires (Yale Food Addiction Scale, Addiction-like Eating Behaviour Scale, The Self-Report Habit Index, The Power of Food Scale, Perceived Stress Scale, Generalized Anxiety Disorder scale, The Patient Health Questionnaire, The Substance Use Risk Profile Scale) online prior to attending a one-off experimental session at the University of Newcastle. On arrival participants will have their height and weight measured by a trained assessor. Participants will complete an IT-mediated task, integrated with physiological measures (heart rate variability, electrodermal activity and pupillary responses) under controlled conditions. This task will involve viewing two x 5min food image paradigms (healthy vs. hyperpalatable foods) on a computer monitor with a 2min wash-out period of neutral images (non-food images) shown in between. Participants will be randomly allocated by block design to group 1 or group 2. Group 1 will view healthy food images first, and hyperpalatable food images second. Group 2 will view hyperpalatable food images first, and healthy food images second. Participants will complete a self-report measure of current hunger (Visual Analogue Scale) before and after viewing the images, and emotional response to images will also be recorded via paper based survey at the end of the session. The session will take approximately 45min to complete and will be administered by an Accredited Practising Dietitian. Image paradigms: food image stimuli to be used in this task has previously been rated in a pilot study (n=10 adults, independent of those involved in the present study) to ensure foods are representative of each of the two categories, and food images are readily identifiable i.e. recognisable and familiar, and shown in an appetising manner for Australian adults. Images are from a licensed database and non-copyrighted sources. Healthy food pictures are based on the five core food groups, and hyperpalatable food pictures based on foods categorised as discretionary choices, outlined in The Australian Guide to Healthy Eating. Intervention adherence: Visual Analogue Scale (VAS) will provide pre and post summary scores to aid in determining if the image paradigms were effective in eliciting appetite and hunger responses. An on/off task will be conducted during the image paradigms to identify non-responders i.e. images will be auto advanced with the exception of 2 timepoints. At 100s and 200s participants will be asked to manually ‘click next’ on the computer screen to enable viewing of the next image. To maintain fidelity each experimental session will be conducted in the same laboratory room and one researcher (Accredited Practising Dietitian) will conduct all the sessions, including anthropometric measurements.

Sponsors

Assoc/Prof Tracy Burrows
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Diagnosis
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years
Healthy volunteers
Yes

Inclusion criteria

Individuals proficient in English with access to the internet and able to visit the University of Newcastle for a one-off visit will be recruited via advertisements on social media platforms (e.g. Facebook, twitter), and advertisements posted on community noticeboards on University of Newcastle campuses.

Exclusion criteria

Individuals with epilepsy, a known heart condition, taking beta blockers, digoxin, or wearing a pacemaker; allergy to adhesive electrode patches or electrode gel used for ECG and GSR procedures. Individuals required to wear glasses with bifocal/varifocal lenses or have any of the following eye conditions: cataracts, prosthetic or bionic eye, amblyopia (commonly referred to as lazy eye). Individuals following a vegetarian diet or specialised diet that will affect their ability to view the food images (e.g. meat and dairy foods).

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026