The hemodynamic changes after brachial plexus block

The hemodynamic changes in brachial artery after infraclavicular brachial plexus block in early and late period.

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12619000360112

Acronym

BBH (Brachial plexus block hemodynamics)

Enrollment

Registered

2019-03-06

Start date

2019-03-08

Completion date

2019-04-08

Last updated

2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary aim of this study is to evaluate the hemodynamic changes after infraclavicular brachial plexus block in early and late period buy using Doppler ultrasound. The secondary aim is to evaluate the relationship between sympathetic, sensorial and motor block in brachial plexus block. The hypothesis of our study is the changes in Volume Flow after brachial nerve block can help us for evaluating sympathetic nerve block.

Interventions

The patients who will receive an infraclavicular nerve block for upper extremity surgery, will be included into the study. All patients will undergo the nerve block in the absence of this study. The Doppler Ultrasound measurements will be taken at 6 different timepoints in all patients; (T0) before the nerve block, (T1) 5 minutes after the nerve block, (T2) 15 minutes after the nerve block, (T3) 30 minutes after the nerve block, (T4) 24 hours after the nerve block, (T5) 48 hours after the nerve block. At every time points the diameter of brachial artery, the Volume Flow, systolic velocity (PSV, cm/s), enddiastolic velocity (EDV, cm/s), mean velocity (Vmean, cm/s), timeaveraged mean velocity (TAVM, cm/s), ratio of PSV and EDV (S/D), resistance index (RI), and pulsatility index (PI) will be measured. The onset time of sensorial block and motor block will be recorded.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

1) 18-65 years old 2) ASA I-II 3) Patient's who will be operated for elective upper extremity operation

Exclusion criteria

1) known allergy to local anesthetic drugs 2) the presence of connective tissue disease 3) neurological or muscle disorders 4) skin infection at the axillary area 5) cardiovascular diseases 6) diabetes mellitus 7) autonomic neuropathy

Outcome results