None listed
Conditions
Brief summary
Chronic nasal obstruction owing to deviated nasal septum leads to increased upper respiratory tract resistance and this leads to chronic hypoxia. It is reported that chronic hypoxia is associated with atherosclerosis. The aim of this study was to investigate the association of septum deviation that causes of the nasal obstruction with carotid intima-media thickness.
Interventions
We include patients who require nasal septal surgery due to nasal septal deviation. The septoplasty was performed in these patients. However, septoplasty operation is not part of our study and postoperative results were not evaluated in this study. The VAS scale and NOSE scale will be performed to the patient and control groups due to evaluate subjective nasal obstruction. The measurements and questionnaire about this study were performed before nasal septal surgery(septoplasty). Blood cholester
We include patients who require nasal septal surgery due to nasal septal deviation. The septoplasty was performed in these patients. However, septoplasty operation is not part of our study and postoperative results were not evaluated in this study. The VAS scale and NOSE scale will be performed to the patient and control groups due to evaluate subjective nasal obstruction. The measurements and questionnaire about this study were performed before nasal septal surgery(septoplasty). Blood cholesterol levels, electrocardiography, and carotid intima-media thickness measurements with B-mode ultrasonography will be performed in both groups. The questionnaires take approximately 10 minutes. Additionally, the electrocardiography and carotid intima-media thickness measurements take approximately 20 minutes.
Sponsors
Selcuk University, Faculty of medicine hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
Individuals who admitted to our outpatient clinic with the complaint of nasal obstruction and were required septoplasty as a control group, volunteer individuals without septum deviation or upper airway obstruction Patients who have BMI under 35 Patients without diagnosed a cardiovascular and pulmonary disease Patients age: 18-65 years
Exclusion criteria
1. patients used smoking and alcohol 2. DM, Hypertension 3. hypercholesterolemia 4. Coronary artery disease 5. History of myocardial infarction, 6. Active infection 7. Asthma, allergic rhinitis 8. A history of cerebrovascular disease 9. Immune-related diseases (eg ankylosing spondylitis, SLE, Behçet) 10. Under 18 years and over 65 years 11. Chronic sinusitis, 12. Cardiac diseases 13. Chronic obstructive pulmonary disease 14. Using ACE inhibitor, Diuretic, angiotensin II receptor blocker and beta blocker 15.Individuals with BMI> 35 16. Patients with a history of known hyperthyroidism 17.Pregnant women, breastfeeding women and patients with poor general condition
Outcome results
None listed