A prospective observational study exploring association between Fractured Neck of Femur (#NOFF) patient's cardiovascular state and postoperative brain oxygen levels and mental state

NIRFlo-NOFF: A prospective observational study exploring association between CI (Cardiac Index) and postoperative cerebral oxygenation and cognition, in the #NOFF (Fractured [#] Neck of Femur) population

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12619000336189

Enrollment

Registered

2019-03-05

Start date

2019-05-01

Completion date

Unknown

Last updated

2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study primarily aims to see how patients having surgery for a common type of hip fracture have the oxygen levels in their brains affected after the operation by changes in their heart strength during the operation. We also want to see how other factors during the operation (blood pressure, and related factors) affect these same patients’ thinking after the operation; as well as seeing how common and how severe abnormally low readings in these factors (and other related heart factors) occur during the operation. We believe that intraoperative reduction in heart strength is related to reduced postoperative brain oxygen levels.

Interventions

Use of intraoperative semi-invasive cardiac index monitoring to examine for episodes of reduced cardiac index; and intraoperative cerebral oxygenation monitoring to examine for episodes of reduced cerebral oxygen levels; then use of postoperative cerebral oxygenation monitoring to examine for episodes of reduced cerebral oxygen levels in the postoperative Day 1-5 period, in the surgical Fractured NOFF population

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

All patients who have received Fractured NOFF surgery and have provided consent

Exclusion criteria

None

Outcome results