None listed
Conditions
Brief summary
The aim of this study is to determine whether contact lens discomfort can be reduced following the use of intense pulsed light to manage Meibomian gland dysfunction. We, the investigators, hypothesise that contact lens discomfort can be reduced by managing Meibomian gland dysfunction with intense pulsed light. This study will occur over 5 visits and participants will be monitored for comfort, Meibomian gland structure and function, inflammation and corneal nerve morphology.
Interventions
The treatment that the participants will receive is administered from a device known as Eye-Light. This device is an intense pulsed light treatment. The Eye-Light treatment will be administered by the co-investigator, a vision science honours student who has been taught the correct method by the company who provided the device. This treatment does not require the use of ultrasound gel during the procedure. The Eye-Light works within the visible light spectra of 600nm. The intensity will be dete
The treatment that the participants will receive is administered from a device known as Eye-Light. This device is an intense pulsed light treatment. The Eye-Light treatment will be administered by the co-investigator, a vision science honours student who has been taught the correct method by the company who provided the device. This treatment does not require the use of ultrasound gel during the procedure. The Eye-Light works within the visible light spectra of 600nm. The intensity will be determined based on the pigment of the participant's skin using the Fitzpatrick grading scale. The participant's Fitzpatrick category will be determined by placing the Eye-Light on the participant's skin. After the participant has been categorised, the device will give an intensity output that will be suitable for the level of pigment the participant has. The intensity varies between 25-65 J/cm2. The treatment will be performed individually to each participant in person, face to face in a clinical room at the School of Optometry and Vision Science, UNSW. It will be performed according to the manufacturer's set requirement. The device will emit 5 flashes of light to the skin below the lower eyelids. Each eye will receive the 5 flashes of light from the nasal to temporal region below the participant's lower eyelid. This procedure will take approximately 5 minutes for both eyes. Both the participant and investigator will wear light protection goggles during the procedure. The participant will receive this treatment 4 times, over the span of 45-days with approximately 15 days between each visit. Each visit will take approximately 1.5 hours.
Sponsors
University of New South Wales
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
- Over 18 years of age - Current contact lens wearers with contact lens discomfort - Evidence of Meibomian gland obstruction (evidenced by a Meibomian gland secretion score of <12 for 15 glands of the lower lid) - CLDEQ-8 score greater than or equal to 12 - Fitzpatrick skin type 1-4
Exclusion criteria
- Ocular medication, category S3 and above - Any systemic or topical medications that will affect ocular physiology or the performance of the lenses e.g. anti-acne medications such as Roaccutane and corticosteroids or immunosuppressant medications such as Hydrocortisone, Prednisolone - Any systemic disease that may affect ocular health e.g. diabetes, Graves disease, and auto-immune diseases such as ankylosing spondylitis, multiple sclerosis, Sjögrens syndrome and systemic lupus erythematosis. Conditions such as systemic hypertension do not automatically exclude prospective subjects - Eye surgery within 12 weeks immediately prior to enrolment for this trial - Previous corneal refractive surgery - Patients with punctal plugs - Patients who tanned in the last 4 weeks - Patients with skin cancer or pigment lesions in the treatment zone - Pregnant or nursing patients
Outcome results
None listed