None listed
Conditions
Brief summary
The recovery of hand and arm function is critical for recovering independence in daily activities. The PREP2 algorithm has been developed and validated at Auckland City Hospital, where it is now carried out by therapy teams as part of their routine clinical care. This study will follow-up patients who have been given a PREP2 prediction as part of their routine care, to evaluate prediction accuracy now that the algorithm is being carried out by clinicians rather than researchers. This study will also ask patients about their experience of being given a prediction for their hand and arm, and whether they think they achieved their predicted outcome, or done better or worse than expected. Additional factors that may modify their outcome will also be evaluated at baseline and during follow-up assessments.
Interventions
The Predict Recovery Potential (PREP2) algorithm predicts hand and arm function outcomes. It can be used within a week of stroke, and makes predictions for 3 months after stroke. For patients with hand and arm weakness after stroke, the first assessment involves evaluating strength in shoulder abduction and finger extension, 3 days after stroke. For most patients, the results of this assessment, combined with their age, is enough information to make the prediction. For some patients, an addition
The Predict Recovery Potential (PREP2) algorithm predicts hand and arm function outcomes. It can be used within a week of stroke, and makes predictions for 3 months after stroke. For patients with hand and arm weakness after stroke, the first assessment involves evaluating strength in shoulder abduction and finger extension, 3 days after stroke. For most patients, the results of this assessment, combined with their age, is enough information to make the prediction. For some patients, an additional test of a key motor pathway in the brain is needed. This test involves using transcranial magnetic stimulation (TMS) to see whether activating the stroke side of the brain can produce a response in the muscles of the affected hand and arm. This test is safe, painless, and non-invasive, and takes around 20 minutes. The results of this test, combined with a clinical score of stroke severity (the National Institutes of Health Stroke Scale) can be used to make a prediction for remaining patients, within 7 days after stroke. The PREP2 algorithm is part of routine clinical care at Auckland City Hospital, where this project will take place. Patients who have a PREP2 prediction will be invited to take part in the project, provided they also meet other inclusion criteria, detailed elsewhere.
Sponsors
University of Auckland
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
A prediction for upper limb functional outcome has been made using the PREP2 (Predict Recovery Potential 2) algorithm by the clinical team responsible for the patient.
Exclusion criteria
Cerebellar stroke Life expectancy less than 12 months Severe cognitive or communication impairment precluding informed consent Residing out of area precluding follow-up
Outcome results
None listed