Use of cadaveric donor blood in liver transplant.

Does use of cadaveric donor blood in orthoptic liver transplant affect blood transfusion rates

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12619000222145

Enrollment

543

Registered

2019-02-14

Start date

2019-02-21

Completion date

2019-12-31

Last updated

2020-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Liver transplant (LT) can be associated with large volume blood loss and subsequent transfusion. Allogenic transfusion of bank blood (BB) has been associated with increased morbidity and mortality. In addition BB has increased cost implications. In our center cadaveric donor blood (DB) is collected in all instate recipients who are ABO and CMV compatible. Briefly DB is collected by inserting a 32Fr chest drain into the inferior vena cava and draining under suction into a cell saver reservoir prior to aortic cross clamping. Following a full cross match the DB is then processed by the cell saver and transfused into the recipient in preference to BB. A retrospective review of transfusion requirements for all patients undergoing LT was conducted to see the effects of DB on transfusion requirements in LT.

Interventions

Patients who underwent orthoptic liver transplant at Austin health between 2009-2018 who received cadaveric donor blood. Patients records will be analysed retrospectively for 30 day outcomes. this time period referrs to 30 following the transplant. Information will be obtained from scanned and electronic hospital records

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Orthoptic liver transplant undertaken at Austin health, Victoria

Exclusion criteria

None

Outcome results