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Measurement of severity of aortic stenosis in patients using aortic acceleration time

Aortic acceleration time in patients with aortic stenosis under general anaesthesia

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12619000206123
Enrollment
300
Registered
2019-02-12
Start date
2015-12-04
Completion date
2019-02-06
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Aortic valve replacement for aortic stenosis is a common procedure. Preoperative transthoracic echocardiography (TTE) and intraoperative transesophageal echocardiography (TOE) are commonly used to guide surgical decision making in the management of aortic stenosis. The maximum aortic valve jet velocity, mean gradient and aortic valve area and aortic acceleration time are normally used to grade the severity of aortic stenosis. The aim of this study was to assess the validity of AAT and the ratio of AAT/ET as a reliable marker of the severity of aortic stenosis using intraoperative transesophageal echocardiography and to compare these findings to those obtained using preoperative transthoracic echocardiography in patients undergoing aortic valve replacement.

Interventions

Retrospective analysis of the continuous wave Doppler signal in patients with aortic stenosis having cardiac surgery, including the aortic acceleration time from our echocardiography database Prosolve. No input from patients is required including repeat scanning, repeat investigations or consent to access records.

Sponsors

Brian Cowie
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients with aortic stenosis having general anaesthesia for an aortic valve replacement where an intraoperative transesophageal echocardiogram was performed

Exclusion criteria

Nil

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026