None listed
Conditions
Brief summary
Intraoperative graft failure is a potentially avoidable major cause of cardiac morbidity and mortality and occurs in up to 3% of grafts (8% of patients) after coronary artery bypass grafting. At present, transit-time flow measurement (TTFM) is the most common intraoperative method for assessing graft function. Our randomized study using the VeriQ system allows to verify the adequacy of the grafts patency at all stages of the operation. In this way the TTFM values of all grafts were recorded intra-operatively in three stages: 1. Immediately after performing of the all distal anastomoses (with proximal snare on target corfonary artery and without it), 2. after the patient was weaned from cardiopulmonary bypass and the hemodynamic condition was assessed as being stable, 3. after heparin inactivation, before chest closure. This allows to control the grafts functionality after performing of each anastomosis and correct the surgical error immediately, without restoring repeat cardiac arrest.
Interventions
A randomized study comparing two groups of patients undergoing coronary artery bypass grafting (CABG) at our institute, where patient first group underwent transit time flow measurements (TTFM) of all bypass grafts using the VeriQ system (MediStim Inc., Oslo, Norway). The TTFM values of all grafts were recorded intra-operatively in three stages: 1. Immediately after performing of the all distal anastomoses (with proximal snare on target corfonary artery and without it), 2. after the patient was
A randomized study comparing two groups of patients undergoing coronary artery bypass grafting (CABG) at our institute, where patient first group underwent transit time flow measurements (TTFM) of all bypass grafts using the VeriQ system (MediStim Inc., Oslo, Norway). The TTFM values of all grafts were recorded intra-operatively in three stages: 1. Immediately after performing of the all distal anastomoses (with proximal snare on target corfonary artery and without it), 2. after the patient was weaned from cardiopulmonary bypass and the hemodynamic condition was assessed as being stable, 3. after heparin inactivation, before chest closure. Materials: Two hundred patients listed for CABG Procedures: All CABGs were performed through a median sternotomy during cardiopulmonary bypass. Full heparinization was given. Who: heart surgeon with 10 years experience Mode of delivery: face to face Number of times: twice / week
Sponsors
Federal State Budgetary Scientific Institution “Tomsk National Research Medical Center of the Russian Academy of Sciences”
Study design
Allocation
Randomised controlled trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
coronary artery disease
Exclusion criteria
Concomitant surgery (valve surgery, aorta surgery)
Outcome results
None listed