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Common ground impedance as a biomarker for post operative hearing loss and dizziness in cochlear implant recipients

Common ground impedance as a biomarker for post operative hearing loss and dizziness in cochlear implant recipients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12619000124134
Enrollment
770
Registered
2019-01-29
Start date
2016-03-01
Completion date
2016-03-01
Last updated
2019-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Spikes in common ground impedances have been associated with loss of residual hearing and the development of post-operative dizziness in cochlear implant recipients. The aim of this trial is to test the use of monitoring common ground impedances to detect these events

Interventions

Hearing loss after cochlear implantation can occur immediately after surgery, or up to 5 years after implantation. Spikes in common ground impedance, i.e., increases in electrode resistivity of greater than 4 kOs, have been associated with a loss of residual hearing and the development of post-operative dizziness in cochlear implant recipients. In this study, we will observe impedances across the electrode array, and associated any spikes observed with medical events. Impedance measurements are

Hearing loss after cochlear implantation can occur immediately after surgery, or up to 5 years after implantation. Spikes in common ground impedance, i.e., increases in electrode resistivity of greater than 4 kOs, have been associated with a loss of residual hearing and the development of post-operative dizziness in cochlear implant recipients. In this study, we will observe impedances across the electrode array, and associated any spikes observed with medical events. Impedance measurements are routinely recorded by cochlear implant audiologists during patient visits to a clinic, therefore these observations are made immediately after implantation, then at 1, 2, 4, and 8 weeks post-implantation, and every 3-6 months thereafter for a total duration of up to 5 years. Medical events will be recorded by the cochlear implant clinic medical staff.

Sponsors

University of Melbourne
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Any adult capable of participating with an audiogram, in whom a clinical recommendation has been made to receive a cochlear implant. Receiving a slim-straight Cochlear CI522 electrode array.

Exclusion criteria

Deafness due to cochlear malformations, including ossification, confirmed by medical examination Pre-existing cochlear implantation Any medical condition contraindicating the use of dexamethasone post-operatively.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026