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Changes in the cuff pressure in newborns in the absence of nitrous oxide

Changes in the cuff pressure in newborns in the absence of nitrous oxide

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12619000109101
Acronym
CFN
Enrollment
30
Registered
2019-01-24
Start date
2016-08-25
Completion date
2017-09-25
Last updated
2019-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

In the current study, we aim to determine the changes in cuff pressure over time in newborns undergoing myelomeningocele repair in prone position under general anesthesia in the absence of N2O.

Interventions

After tracheal intubation with a high volume low pressure cuffed ETT (Nextech®, Istanbul, Turkey), the cuff was inflated until there is no audible gas leak. An anaesthesiologist checked the gas leak using a stethoscope guided inflation over the trachea while holding continuous positive airway pressure of 20–25 cm H2O The ETT cuff pressures were monitored simultaneously with a cuff manometer and pressure transducer . The measurements were observed continuously. When the cuff pressure is noted to

After tracheal intubation with a high volume low pressure cuffed ETT (Nextech®, Istanbul, Turkey), the cuff was inflated until there is no audible gas leak. An anaesthesiologist checked the gas leak using a stethoscope guided inflation over the trachea while holding continuous positive airway pressure of 20–25 cm H2O The ETT cuff pressures were monitored simultaneously with a cuff manometer and pressure transducer . The measurements were observed continuously. When the cuff pressure is noted to exceed 15 cmH2O, the cuff was deflated immediately to less than 15 cmH2O. The time when the correction occurred, the time interval between corrections and the number of corrections during surgery were recorded. The baseline cuff pressure was assessed in the supine position after which time a second measurement was made in the prone position. A blind anesthesiologist checked and recorded the cuff pressure. If the pressure was between 10-15 cmH2O, no intervention was performed. If the pressure exceeded 15 cmH2O, the cuff pressure was managed as described above. The cuff pressures were compared over time within patients. In addition, heart rate, end-tidal CO2, temperature and peak airway pressure were recorded every 15 min.

Sponsors

Kemal Tolga Saracoglu
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
No minimum to 28 Days
Healthy volunteers
No

Inclusion criteria

Newborns Undergoing surgery under general anesthesia

Exclusion criteria

Patients whom could not have obtained informed constent

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026