None listed
Conditions
Brief summary
An open label randomised controlled trial which will be conducted in student clinic and comparing the efficacy of oral azithromycin and oral doxycycline on moderate acne plus it will see the difference in quality of life scale in both groups before and after treatment. A total of 200 moderate acne patients, males and females, will be included in the study, 100 patients in each arm. The gender and age will be distributed equally between the two groups. They will be followed for 3 months with an assessment in the improvement in acne severity scale every month from the start of the study. The response to treatment will be assessed by using the difference in acne severity scale before treatment and after 3 months of treatment.
Interventions
azithromycin capsules 500 mg once daily after food for 3 days , then 500 mg once a week after food (every Friday) for total of 12 weeks.
The prescription will be given in a monthly basis, each time the students will be asked about any remaining capsules.
Sponsors
Sultan Qaboos University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
17 Years to 25 Years
Healthy volunteers
No
Inclusion criteria
university students diagnosed with moderate acne by Acne Severity Scale
Exclusion criteria
1- Patients on antibiotics for other reasons in less than one month. 2- Pregnant ladies 3- Patients on topical anti-acne treatment 4- Patients with liver disease 5- Patients on topical or oral steroids 6- Patients on oral contraceptives
Outcome results
None listed