Duration of operation and cross-clamp time relative to cystatin C level of early-onset renal insufficiency in patients undergoing coronary artery bypass graft surgery,

1-2 µg / kg of fentanyl, 2-3 mg / kg of propofol and 0.6 mg / kg of rocuronium will be administered intravenously during induction of anesthesia. After 2 minutes the patient will be intubated. Central vein catheterization will be performed from right jugular vein. At this time, 5 ml of blood will be taken for cystatin C level and sent to the laboratory. Anticoagulation with 300 IU / kg heparin will be administered intravenously to enter the cardiopulmonary bypass. ACT (activated clotting time) values will be checked with ACT measurement device by periodic measurements for 30 minutes until cardiopulmonary bypass is stopped and cannulas are withdrawn. Hourly urine output, mediastinal drainage volume, duration of extubation will be noted. Blood samples for hemogram, BUN, creatine and cystatin C measurements will be taken at the 2nd and 24th hours postoperatively and sent to the laboratory. Blood samples taken for cystatin C will be stored at -80 ° C until assay time after centrifugation. Anesthesists will perform processes in the operating room and intensive care unit. Bioscience specialist will perform the processes in the laboratory Bypass operation will last for almost 3-4 hours and in intensive care unit hourly urine output, mediastinal drainage volume, duration of extubation, intraoperative and postoperative blood and blood product amounts given in the first 24 hours will be noted by anesthesists.