None listed
Conditions
Brief summary
Platinum C will collect information on people who have hepatitis C virus infection and the effects of hepatitis C treatment. We aim to work out how effective new hepatitis C treatments are, and to find out what things influence their outcomes, including the type of treatment they have, how well they adhere to treatment, and major life disruptions. We aim to understand which people are unlikely to take all of their hepatitis C medications and if and how this affects their response to treatment. We will ask some additional questions about general well-being before, during and after treatment. We expect this information will help researchers find ways to help more people to get tested, treated and cured of hepatitis C infection.
Interventions
This study will enrol participants with hepatitis C virus (HCV) infection from participating sites. Active HCV infection will be established by confirming the presence of HCV RNA in blood. Those enrolled will agree to allow the systematic collection of their demographic, lifestyle, treatment, outcome, and other relevant clinical data to better inform the future management of the condition. The primary outcome is virological cure, as evidenced by a sustained virological response (SVR) defined as
This study will enrol participants with hepatitis C virus (HCV) infection from participating sites. Active HCV infection will be established by confirming the presence of HCV RNA in blood. Those enrolled will agree to allow the systematic collection of their demographic, lifestyle, treatment, outcome, and other relevant clinical data to better inform the future management of the condition. The primary outcome is virological cure, as evidenced by a sustained virological response (SVR) defined as a negative HCV PCR result 6 to 18 months after initial prescription of antiviral therapy, and no less than 12 weeks after the end of treatment. Participants within the study will have the option to participate in medication adherence monitoring and a quality of life assessment (EQ-5L-5D).
Sponsors
Telethon Kids Institute
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
To be eligible, a participant must meet the following criteria: 1. Evidence of active HCV infection (HCV RNA detected) within the preceding 3 months 2. Adult 18 years of age or above
Exclusion criteria
A potentially eligible individual will be excluded from participation if either of the following criteria are met: 1. Already receiving direct-acting antiviral medication for HCV infection 2. Unable or unwilling to provide informed consent
Outcome results
None listed