None listed
Conditions
Brief summary
Background and Goal of study: Ventilator-associated pneumonia (VAP) is an important matter in patients careed in Intensive Care Units, having an increased burden. The noble metal alloy coated endotracheal tubes (ETTs) have been designed to prevent bacterial colonization and to reduce VAP, but their efficacy, benefits and disadvantages available data are still full of controversy. The objective was to determine whether VAP incidence can be influenced using noble metal alloy ETTs in patients admitted for acute drug poisoning requiring mechanical ventilation. Material and Methods: A randomized conrolled study was conducted in Critical Care Toxicology Unit, in Bucharest Clinical Emergency Hospital. We enrolled all intubated patients for coma due to drug poisoning, considering the profile of the clinic. All patients were assigned to undergo either uncoated ETTs or noble metal alloy-coated ETTs. Primary outcomes were VAP appearance at 5 days and endotracheal microbiology analysis, while sepsis incidence was secondary outcome.
Interventions
The intervention group received noble metal alloy coated endotracheal tube used in patients admitted in the toxicology critical care, requiring mechanical ventilation, performed either by emergency doctors and critical care doctors.
endotracheal tube is a device used to protect airway in patients unable to maintain their vital signs.
the duration of intubation depends upon the general status (evaluated by research supervision), but the outcomes were evaluates after 5 days of intervention. there
The intervention group received noble metal alloy coated endotracheal tube used in patients admitted in the toxicology critical care, requiring mechanical ventilation, performed either by emergency doctors and critical care doctors. endotracheal tube is a device used to protect airway in patients unable to maintain their vital signs. the duration of intubation depends upon the general status (evaluated by research supervision), but the outcomes were evaluates after 5 days of intervention. there is no min or max duration of time for the alloy tube to stay in place
Sponsors
tincu radu ciprian
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
We included in the study all subjects that needed mechanical ventilation for acute drug poisoning.
Exclusion criteria
The exclusion criteria were: trauma patients, inter hospital transferred patients, family refusal.
Outcome results
None listed