None listed
Conditions
Brief summary
Multiple sclerosis belongs to the progressive diseases of the central nervous system. The lesions concern the structure of myelin sheaths in the brain and spinal cord. The main symptoms of the disease are limb paresis, sensory disturbances, visual disturbances, impaired motor coordination and balance, gait disturbances, fatigability and depression. Based on the review of domestic and foreign literature, it can be concluded that there are no studies on the relationship between muscular strength, degree of fatigue, gait and balance among people with multiple sclerosis depending on the disability level in the Extended Disability Status Scale (EDSS). The aim of the study will be to assess the relationship between muscular strength of the lower limbs and body balance, gait and fatigue in people with multiple sclerosis, taking into account the degree of disability described in the EDSS scale. Parameters assessed include: gait speed, independent mobility, body balance, strength of lower limbs and fatigue. - gait speed - 10 meter walk test and Timed 25-Foot Walk Test - independent mobility (risk of falls) - Time Up and Go Test- muscular strength in isokinetic conditions for extensors and flexors of the knee joint - Biodex System 4 Pro - balance - computer dynamic posturography. The test will be performed at Neurocom's Smart Equi Test - gait efficiency - 6 minute walk test
Interventions
The estimated time of examination for one patient is 2 hours. Patients with multiple sclerosis will participate in the study. The main aim of the study is to assess the relationship between muscular strength, balance, gait and the level of fatigue in people suffering from multiple sclerosis. The specific aims are: to assess the variability of isotonic contraction of extensor and flexors muscles of the knee joint depending on the severity of the disease symptoms; assessment of the relationship be
The estimated time of examination for one patient is 2 hours. Patients with multiple sclerosis will participate in the study. The main aim of the study is to assess the relationship between muscular strength, balance, gait and the level of fatigue in people suffering from multiple sclerosis. The specific aims are: to assess the variability of isotonic contraction of extensor and flexors muscles of the knee joint depending on the severity of the disease symptoms; assessment of the relationship between the muscle strength of extensors and flexors of the knee joint and the balance and stability of the persons qualified for the tests; assessment of any and maximum gait speed depending on the severity of the disease process and depending on the strength of flexor and extensor muscles of the knee joints in people with multiple sclerosis; assessment of gait performance depending on the severity of the disease process and depending on the strength of the flexor and extensor muscles of the knee joints in people with multiple sclerosis; assessment of the relationship between fatigue and the strength of the extensor and flexor muscles of the knee joints. Research will take place at the Natural and Medical Research Center of Innovation of the University of Rzeszów. The following parameters will be used to assess the patient's condition: gait speed (measured using the 10 meter walk test and the Timed 25-Foot Walk Test); independent mobility (risk of falls) - measured using Time Up and Go Test; strength of the lower limb muscles - the measurement will be made using the Biodex System 4 Pro device; body balance (measured using the Neurocom Smart Equi Test); gait efficiency - a 6-min walk test will be performed; fatigue level - using the Fatigue Severity Scale (FSS) scale. At each test, the patient will be accompanied by a physiotherapist for the sake of protection.
Sponsors
University of Rzeszow
Eligibility
Sex/Gender
All
Age
25 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
Participants with Multiple Sclerosis (during remission), Expanded Disability Status Scale (EDSS) (2-6), able to walk independently (without assistance of other people, with orthopedic equipment if necessary).
Exclusion criteria
the period of disease relapse, cognitive impairment that hinders understanding and acting in accordance with instructions (Mini Mental Scale below 24), unstable medical condition, contractures and orthopedic diseases of the lower limbs, coexisting other diseases disturbing gait or body balance.
Outcome results
None listed