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Mind-body interventions in patients with multiple sclerosis

Efficacy of mind-body interventions in patients with multiple sclerosis and walking limitation

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12618002024224
Enrollment
7
Registered
2018-12-18
Start date
2017-10-31
Completion date
2017-11-09
Last updated
2021-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

In this study we intend to prove if the search and modify (or restructuring) of a possible "emotional cause" of the disease during an hypnotic trance as well as to know the possible causes and solutions of the disease according to the patients´ unconscious, improves the disability (measured with the expanded disability status scale, EDSS) of patients with multiple sclerosis and walking limitation (with the need from a walking stick to a wheelchair to move), as well as the quality of life. In this study the patients have been followed for a period of 10 weeks before the randomization in 2 intervention groups, the randomization was performed according to the disability (measured by the EDSS), during these 10 weeks the endpoint variables (the EDSS and the quality of life measured by the SF-36 health survey questionnaire) have been measured in order to know the evolution of each patient without any mind-body intervention. The experimental group is the hypnosis group and the active control group is the healing imagery group, in the experimental group the patients will receive an individualized hypnotic therapy with an experimented professional that will search a possible emotional cause of the disease in the half of the sessions (5 sessions) and in the other half of the sessions will do healing imagery technique during the trance, each session will be performed once a week. In the active control group, the 10 group weekly sessions will be only directed to healing imagery. The endpoint variables will be measured at the end of the 10 week intervention and a comparison of the differences in these variables between groups will be performed.

Interventions

The patients included in the hypnoanalysis group should assist to 11 sessions which consisted in 1 interview and 10 hypnotic sessions that lasted around 1 hour (1 weekly) performed as follow: 1) the first day consisted in a semi-structured interview of questions related with their life, before, during and after the diagnosis, a possible emotional cause of the disease and impressive events before the disease; 2) the second session was performed in hypnosis and consisted in the search in the “book

The patients included in the hypnoanalysis group should assist to 11 sessions which consisted in 1 interview and 10 hypnotic sessions that lasted around 1 hour (1 weekly) performed as follow: 1) the first day consisted in a semi-structured interview of questions related with their life, before, during and after the diagnosis, a possible emotional cause of the disease and impressive events before the disease; 2) the second session was performed in hypnosis and consisted in the search in the “book of their life” of at least for 5 events related with the cause of the disease and in the restructuring of at least one of the events that apparently still affected the patient, these restructuring was based in the reimprinting technique described by Dilts et al.(this technique consisted in modify the traumatic scene by identifying the resources that the patients and the others involved ones needed, and changing the possible beliefs created in the event); 3) the third session consisted in calling the responsible part of the disease and asking it for the cause(s) of the disease and possible solutions of it and repeat each possible solution 100 times in their mind and if they agreed they made a commitment with that part to change in that aspects; 4) the fourth day consisted in talking with the inner child and with their perfect or ideal version and asking them what they needed to be happy (in the case of the child) and to be like them (in the case of their perfect version) and they made a commitment with both parties to change what they ask for, finally they performed a final fusion among them and the child and the perfect version; 5) the fifth session consisted in searching in the book of healing for all possible actions that will lead to the physical improvement of disease and repeat them 100 times; 6) the sixth session consisted in a script related to mind-body interconnection based in a script of Satir ; 7) the seventh session consisted in a script that gave them to a motivating future, based in a script of Virginia Satir; 8) the eight session consisted in visualizing the brain and the immunology system before the disease and now, looking for differences and asking them what they should do to be like before the disease and make a commitment with that cells in doing what they ask them; 9) the ninth session consisted in repeating the script related to mind-body interconnection ; 10) the tenth session consisted in comparing 3 events that had predisposed to the disease with events that had predisposed to healing in their life and identify the abilities that will help them to perform the second ones and repeat that abilities 100 times in their mind (Supplementary file 3); 11) the eleventh session consisted in repeating the script of a motivating future. In addition 15 minutes of healing imagery were also included in at least in 5 sessions. The same person, performed all sessions and after the post-intervention measurement, the patients were given the transcripts of their hypnotic trances. It is important to mention that all answers were specified with more questions until a clear answer was provided (i.e.: if the answer was “because I was afraid” the next question was “What were you afraid of?”).

Sponsors

Aniel Jessica Leticia Brambila Tapia
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients older than 18 years Patients with multiple sclerosis diagnosed with the McDonald criteria Patients with walking limitation, with at least 6 points in the Expanded disability status scale (EDSS score equal or more than 6) Patients that want voluntarily participate in the study

Exclusion criteria

Patients with cognitive impairment that prevent to perform the interventions

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 25, 2026