None listed
Conditions
Brief summary
The purpose of this study is to assess whether there is a role of non-anaemic iron deficiency in colorectal cancer. Who is it for? You may be eligible for this study if you are an adult who has been diagnosed with colorectal cancer, and are also scheduled to undergo surgery for colorectal cancer. Study details Participants will continue with their current cancer treatment plan, and answer questionnaires in regards to their health over a 3-month period following their surgery. The results of certain blood tests will also be used. These blood tests are taken as part of routine care. You will not be required to have additional blood tests if you are participating in this study. The results of participants with iron deficiency prior to their surgery will be compared to those without iron deficiency. We hope that this study will show that iron replete patients have improved recovery after surgery for colorectal cancer, and enable more widespread research into the role of iron treatments prior to this sort of surgery.
Interventions
This is a non-interventional study. Patients will not receive any treatment additional to current standard of care. The "intervention" group will be patients undergoing surgery for colorectal cancer who are non-anaemic and iron deficient. They will be followed from the time of surgery until 90 days after the primary surgical procedure.
Sponsors
Department of Critical Care, University of Melbourne
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patient scheduled to undergo major elective surgery for colorectal cancer (laparoscopic or open colectomy, anterior resection or abdominoperineal resection).
Exclusion criteria
Pregnancy Age < 18 years Iron supplementation (oral or parenteral) or EPO therapy received or planned between baseline preoperative blood tests and operation Haemoglobinopathy (thalassaemia or sickle cell) Bone marrow disease or haemochromatosis End-stage renal failure requiring dialysis Pre-operative anaemia (female: Hb < 120g/L, male: Hb < 130 g/L) Pelvic exenteration or secondary surgical procedure (i.e. bowel resection AND liver resection during the same surgical procedure)
Outcome results
None listed