This study investigates the relevance of male age and male factors impacting on the chance of live births from in vitro fertilization treatment cycles

This retrospective cohort study investigates the outcomes of 1280 in vitro fertilization treatment cycles with respect to considering the relevance of male age and semen parameters

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12618001820291

Enrollment

1280

Registered

2018-11-08

Start date

2008-04-01

Completion date

2017-11-30

Last updated

2018-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study looks at the male age effect on the sperm parameters and the clinical pregnancy and live birth rates in an IVF cycle. We included heterozygous couples using autologous gametes in their first fresh IVF cycle. We only included patients who had single embryo transfer.

Interventions

This study looks at the outcomes for couples with infertility where in vitro fertilisation treatment was applied. The study was retrospective and conducted over the period 1st April 2008 to 30th November 2017. During this period 4173 autologous treatment cycles by in vitro fertilisation were undertaken and, after exclusions, this study focussed on 1280 treatment cycles examining the effect of male age and sperm parameters on clinical pregnancy and live birth rates in fresh IVF cycles.

Eligibility

Sex/Gender

All

Age

22 Years to 64 Years

Healthy volunteers

Inclusion criteria

all first fresh autologous cycles in heterozygous couples undergoing IVF with single embryo transfer. Female ages ranged 22 years to 48 years Male ages ranged 23 years to 64 years

Exclusion criteria

donor cycles using donor gametes frozen cycles natural cycles assessment cycles and other types of fertility treatments such as IUI azoospermic males

Outcome results