None listed
Conditions
Brief summary
Sarcopenia is the age-related loss of skeletal muscle mass and strength. The combined loss of muscle with excess adiposity is called sarcopenic-obesity. The focus of these conditions has been in those over 60 years of age. However, the progressive loss of skeletal muscle mass and strength begins in middle age, when obesity also peaks. Therefore, the aim of this research is to assess the effects of a high-intensity exercise to reverse early onset (pro-dromal) sarcopenia and sarcopenic-obesity in early middle age.
Interventions
The intervention includes a 40-week randomized controlled trial of high intensity aerobic and resistance interval training (HIART). The 40-week intervention involves 20 weeks of training followed by a 20-week follow-up. Each training session will start with a warming up, then the HIART training and ends with a cool-down. The HIART training involves three phases, set up as a circuit. The three phases are;
1) a “power” phase, consisting of two whole-body resistance exercises (e.g. jumping jacks,
The intervention includes a 40-week randomized controlled trial of high intensity aerobic and resistance interval training (HIART). The 40-week intervention involves 20 weeks of training followed by a 20-week follow-up. Each training session will start with a warming up, then the HIART training and ends with a cool-down. The HIART training involves three phases, set up as a circuit. The three phases are; 1) a “power” phase, consisting of two whole-body resistance exercises (e.g. jumping jacks, lunges, push-ups, squats) 2) 10 minutes of high-intensity cardiorespiratory cycling 3) a resistance phase, consisting of two resistance exercises with or without free weights Training load will be self-selected from designated options but participants will be encouraged to choose a wattage that will ensure that their heart rate reaches 85% of their maximum heart rate during the high-intensity peaks and does not drop below 60% of their maximum heart rate during the low-intensity periods. All training sessions are group-based, with a maximum of 9 people in each group. All training sessions will be provided by a trained and experienced physiotherapist. In order to maximize adherence, participants will receive an email reminder 24 hours before the exercise session. Adherence will be monitored using attendance checklists by the physiotherapist.
Sponsors
University of Otago
Study design
Allocation
Randomised controlled trial
Primary purpose
Prevention
Eligibility
Sex/Gender
All
Age
40 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
Inclusion criteria will include otherwise healthy men and women aged between 40 and 50 years of age, who are not meeting the physical activity guidelines (2.5 hours a week of moderate activity) and are at risk of developing low muscle mass. Being at risk of developing low muscle mass will be assessed using a newly developed screening tool.
Exclusion criteria
Participants will be excluded if they: 1) Take medications known to affect body composition or heart rate; 2) Are diagnosed with moderate or severe hypertension; 3) Are pregnant or breastfeeding, or planning on becoming pregnant during the intervention; 4) Have a previous diagnosis or symptoms of cardiovascular disease or other serious medical condition; 5) Screened out after exercise safety screening; 6) Weigh more than 159.9 kg (weight limit of the DXA scanner); 7) Live outside of metropolitan Dunedin; 8) Are unable to communicate in English or te reo Maori.
Outcome results
None listed