The effect of Virgin coconut oil on cholesterol and glucose level among acute coronary syndrome patients.

The effect of Virgin coconut oil on lipid profile and glucose level among acute coronary syndrome patients : A single blind study

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12618001736235

Acronym

VCO Study

Enrollment

Registered

2018-10-22

Start date

2018-03-05

Completion date

2018-03-09

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A randomized single blind study was conducted between from March 2018 to May 2018 to investigate the effect of virgin coconut oil (VCO) on serum lipid profile (cholesterol) on patients with acute coronary syndrome patients’ (ACS). The study will provide new evidence on the ability of the VCO to reduce cholesterol and glucose level for ACS patients. The findings could help in improving patients’ quality of life which in line one of the Malaysia National Research Agenda.

Interventions

RCT was conducted among 70 Acute coronary sundrome (ACS) patients for 30 days. Participants were randomly be assigned into the intervention group and control group by using simple random sampling. Participant in group A were received there bottles contain of 100 pieces of Virgin coconut oil (VCO) soft gels each bottles with label A. Participants in group A were instructed to ingest 5 capsules of VCO twice per day (0.5ml/capsule = 10 capsules/5 mls ) for 30 days. They were also continuing routine treatment including consuming Statin medication. While group B remain routine treatment and Statin medication. After 30 days all subjects were followed-up in the ward for blood taking (Fasting blood sugar and Fasting serum lipid) and anthropometry measurement. They were instructed to fast for at least 10 hour before blood taking. Group A were instructed to bring back the empty label A containers and the amount left was measured in order to monitor the compliance.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Educational / counselling / training

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Healthy volunteers

Inclusion criteria

1. Both gender 2. ACS patients receiving Cardiac rehabilitation program (CRP) program 3. ACS patients with Statin 4. ACS patients understand English and Malay language

Exclusion criteria

1. ACS patients with renal failure 2. ACS patients with liver failure 3. ACS patients with pregnancy

Outcome results