None listed
Conditions
Brief summary
Clostridium difficile infection (CDI) is a major hospital-acquired infection capable of causing complications ranging from diarrhoea to severe infection. Two years ago Dunedin Hospital, which historically has low rates of CDI, introduced a PCR test which identifies the genes which produce the CD toxin. We also perform an immunoassay test to directly identify the toxin. We aim to assess the impact of this new test on the incidence of diagnosis of CDI, and to assess the clinical significance of the combined result of a PCR gene positive test and an immunoassay toxin negative test.
Interventions
Clostridium difficile infection (CDI) is a major hospital-acquired infection capable of causing complications ranging from diarrhoea to severe infection. In 2016 Dunedin Hospital, which historically has low rates of CDI, introduced a PCR test which identifies the genes which produce the CD toxin. We also perform an immunoassay test to directly identify the toxin. We aim to assess the impact of this new test on the incidence of diagnosis of CDI, and to assess the clinical significance of the comb
Clostridium difficile infection (CDI) is a major hospital-acquired infection capable of causing complications ranging from diarrhoea to severe infection. In 2016 Dunedin Hospital, which historically has low rates of CDI, introduced a PCR test which identifies the genes which produce the CD toxin. We also perform an immunoassay test to directly identify the toxin. We aim to assess the impact of this new test on the incidence of diagnosis of CDI, and to assess the clinical significance of the combined result of a PCR gene positive test and an immunoassay toxin negative test. This will be done using hospital records for the period from 2014-2018.
Sponsors
Dunedin School of Medicine, University of Otago
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients who have had a diagnosis of a Clostridium difficile infection at Dunedin Hospital from 2014-2018
Exclusion criteria
not applicable
Outcome results
None listed