None listed
Conditions
Brief summary
The main aim of this study is to investigate if salmon structure is important in fat metabolism. To test this we will be undertaking a single meal crossover study in healthy female participants and fat-induced blood markers measured.
Interventions
The 16 participants will attend in groups of 1-3. Each participant will be invited to attend 3 study visits with a washout period of ~7 days. In each of the study visits, participants will arrive at the research unit in Massey university, Auckland. They will be given a meal containing potatoes and 40g of fat from cream, Each meal will also contain ~120g of intact salmon, homogenized salmon or salmon oil plus deffatted salmon.
Participants will be asked to finish the meal within 15 minutes and
The 16 participants will attend in groups of 1-3. Each participant will be invited to attend 3 study visits with a washout period of ~7 days. In each of the study visits, participants will arrive at the research unit in Massey university, Auckland. They will be given a meal containing potatoes and 40g of fat from cream, Each meal will also contain ~120g of intact salmon, homogenized salmon or salmon oil plus deffatted salmon. Participants will be asked to finish the meal within 15 minutes and adherence monitored via direct supervision. The meals will be matched for moisture. All meals contain around 550 kcals (foodworks 9, 2016 NZ food files). A cannula will be inserted into the forearm of the participant and blood will be taken before the meal is consumed or 30 minutes, 1, 2, 3, 4 and 6 hours after the meal is consumed.
Sponsors
Massey University
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject)
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
A healthy female aged between 18 and 45 years, with a regular menstrual cycle and a normal body weight (body mass index between 18 and 30 kg/m2) at initial assessment.
Exclusion criteria
• Are pregnant or trying to get pregnant (during the study period) • Suffer from cancer, HIV/Aids or inflammatory bowel disease • Think you have a weak immune system • Use herbal supplements or fish oil regularly • Take immunosuppressive drugs • Recently donated blood or have a fear of needles • Smoke • Take any lipid lowering drugs or supplements or hypertensive drugs • Are dieting or have any eating disorders • Have a dislike, intolerance or allergy to dairy and/or fish • Have a history of heart disease • Have a history of diabetes, hypertension, high cholesterol • Have a history of gastrointestinal disorder or liver disease • Vigorously active
Outcome results
None listed