None listed
Conditions
Brief summary
Mix thickness burns of face usually treated conservatively. Topical application of ointment alone is usually combersome and sometimes due to secondary infection led to increase in depth of burns. Amnion is a form of biological dressing and does not require any change of dressing when applied on face. In this study we will compare the results of traditional treatment with amnion application on the face.
Interventions
Amnion will be obtained after informed consent from enrolled healthy expecting mothers undergoing C-section, with no co-morbidities or infections, testing negative for HBV, HCV and HIV. Meconium-contaminated placenta would be discarded. Amnion will be separated from placenta by washing with large volumes of normal saline. Membranes would then be transferred to another container containing 70% glycerol and refrigerated at 4 degree Centigrade. For Group A, Amnion will be retrieved from the fridge, dipped in normal saline for 10 min to remove glycerol and applied to the cleaned and dried facial burns by the primary investigator, ensuring no air bubbles between it and the bed. Topical antibiotic onitment (Polyax Ointment - Glaxosmithkline) will be applied three times a day upto 2 atleast 2 weeks upto 1 month. No secondary dressing will be applied. The amnion will remain there till the burn wound epithelization atleast 2 weeks and up to 1 month.
Sponsors
Muhammad Umar Asif
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
10 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
1. All patients with partial thickness facial burns (as per-operational definition). 2. Duration of burn <72 hours
Exclusion criteria
1. TBSA <11% and >40%. 2. Patients with full thickness burns as assessed clinically
Outcome results
None listed