None listed
Conditions
Brief summary
Creatine is a dietary metabolite responsible for buffering quick changes in cellular energy supply and demand. We hypothesise that maintaining a particular level of circulating creatine during pregnancy can help ensure proper development and function of the placenta, and assist in fetal growth and development. The Creatine and Pregnancy Outcomes Study - CPO - has been specifically designed to provide thorough understanding of maternal creatine metabolism across gestation, including the placenta's contribution to maternal and fetal creatine levels. We will also collect nutrition data to enhance our understanding of how differing dietary habits over pregnancy may impact on creatine levels, and if these differences affect pregnancy outcomes.
Interventions
This is an observational study across gestation. It involves the collection of blood and urine samples, and dietary information from pregnant women at 6 time-points during gestation, [1] 10-20 weeks, [2] 21-23 weeks, [3] 24-27 weeks, [4] 28-32 weeks, [5] 33-36 weeks & [6] Birth.
Sponsors
Dr Stacey Ellery
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
Pregnant women attending low risk antenatal clinics and planning to birth at Monash Health, Melbourne, Victoria
Exclusion criteria
Women who have a known significant pre-existing major medical condition or who have been assessed as high risk or have a multiple pregnancy
Outcome results
None listed