Skip to content

Strengthening health systems to improve tuberculosis contact screening and management in Timika, Indonesia

Strengthening health systems to improve tuberculosis contact screening and management in Timika, Indonesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12618001503213
Acronym
Short title: Preventing TB in children in Timika (PeTiT study)
Enrollment
200
Registered
2018-09-06
Start date
2017-09-17
Completion date
2019-09-30
Last updated
2018-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Prevention of tuberculosis (TB) among at-risk individuals is recognised to be a global priority. However there is a major policy-practice gap, with limited implementation of contact investigation and management in Timika, Papua. In this health systems strengthening project, an intervention will be applied at TB treatment facilities in Timika to increase adherence to the national guideline. The intervention comprises training, continuous quality improvement processes, a social media discussion forum and awareness-raising activities and promotional materials. The rates of implementation of the contact management pathway (identifying new TB cases, identifying people eligible for treatment, commencing treatment and completing treatment) will be compared during the two-year intervention period with respective rates during the baseline period.

Interventions

This is a mixed-methods, before-and-after, multi-site, intervention study to implement the WHO tuberculosis contact management and investigation policy. Activities fulfill the definition of a complex intervention Setting: Mimika district, Papua Province, Indonesia. Five healthcare facilities will participate in phase 1 and seven in phase 2 of the policy roll out. Physical or informational materials that will be used in the intervention: - Indonesian Policy on TB Contact management - Resource

This is a mixed-methods, before-and-after, multi-site, intervention study to implement the WHO tuberculosis contact management and investigation policy. Activities fulfill the definition of a complex intervention Setting: Mimika district, Papua Province, Indonesia. Five healthcare facilities will participate in phase 1 and seven in phase 2 of the policy roll out. Physical or informational materials that will be used in the intervention: - Indonesian Policy on TB Contact management - Resources (paper, video) designed for patients Procedures, activities, and/or processes used: 1. Training Training will be provided by the doctoral research student and Indonesian medical experts in prevention and management of TB, in the form of workshops for healthcare providers from the five primary participating sites, and any additional healthcare providers from other sites who wish to attend (including the follow-up sites). Training sessions will be free of charge and during usual working hours, by arrangement with management at their respective workplaces. The elements of TB contact investigation and management policy will be taught, including practical implications and logistics of rolling this out at each clinic. Hands-on training will also be provided in the medical or nursing skills required to implement the policy, such as collection of induced sputum from contacts found to have symptoms of TB, and accurate weight-based dosing of isoniazid. Pre- and post-training tests will be conducted to understand knowledge and measure the effectiveness of the training. Continuous quality improvement 2. Continuous quality improvement (CQI) forms a cornerstone of implementation of this project at the five initial sites. CQI cycles will be implemented whereby every three months (approximately, coinciding with study staff and participant availability), a workshop will be held to allow staff at the five sites to engage pro-actively with the data they routinely collect and report (but rarely review) on TB outcomes and contact management. Plots and pictograms will be generated that are easy for healthcare providers to understand, showing progress in key performance indicators, such as the proportion of contacts who are investigated, and the proportion of eligible contacts who are commenced on IPT. Discussions to congratulate and motivate staff will be undertaken, and challenges will be workshopped. Where appropriate, recommendations arising from these CQI workshops to address challenges in policy implementation (e.g. staffing allocations, access to transport for outreach services) will be communicated by the doctoral researcher to the District Health Authority. The approach will draw on lessons learned in previous research using CQI cycles in primary care to improve adherence to guidelines. 3. Social media discussion forum Mentoring and clinical support will be provided via a ‘WhatsApp’ group. ‘WhatsApp Messenger’ is the most widely-used, freely-available communication application in Indonesia, accessible from mobile devises or desktop computers. It allows sharing of text messages, photographs, documents, voice calls and video calls. Healthcare providers participating in the study at both initial and follow-up sites will be invited to the ‘WhatsApp’ group moderated by the doctoral research student and with access to an Indonesian TB specialist. This will provide a forum for information sharing relevant to the study, and participants will be able to post questions relating to the contact management policy or other aspects of TB care. 3. Awareness-raising activities and promotional materials Posters and information brochures have been developed by the project team in the main local Papuan language and Bahasa Indonesian. These provide pictures and writing about latent TB, how it can progress to active TB, and how preventive treatment can stop it. Who will deliver the intervention: - PhD student with medical background and masters in public health working alongside District Health Authority and staff at healthcare facilities. Mode of delivery: - face to face training and CQI workshops - social media information and support group Number of times the intervention will be delivered: - CQI workshops for 2 hours every 3 months, face to face using data generated by healthcare facilities on TB key performance indicators - Training, social media support, visits to healthcare facilities to provide motivation and support - ongoing throughout the 2-year intervention period Location where the intervention occurs: - Five primary sites: 2 hospitals and 3 Puskesmas (primary healthcare facilities) - Seven secondary sites (7 Puskesmas) which will receive training and support from staff at the first 5 sites Study design: This is a mixed-methods intervention study. Interrupted time series analysis will be used to analyse longitudinal data before, during and after the intervention. Study periods comprise a 26-month retrospective baseline period from 1 January 2015 – 31 March 2017, a 5-month prospective baseline period with active data cleaning and validation, a 24-month intervention period (including activities at initial and follow-up sites) and a 12-month sustainability period. These periods were pragmatically chosen based on data and resource availability. These periods were chosen pragmatically on the basis of available data and timing of study commencement. An annotated line graph will be produced to show the primary outcome (numbers of people completing isoniazid preventive therapy) over time, with the timing of key study activities, external activities and environmental influences being indicated on the graph. A two-tiered approach to the intervention will be used to provide an additional measure of sustainability: intensive activities will take place with the five initial participating sites, then healthcare providers at these sites will then be trained (using a ‘train the trainer’ approach) to share their knowledge with the seven follow-up sites.

Sponsors

Menzies School of Health Research
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Healthy volunteers
Yes

Inclusion criteria

Quantitative study: - people with active TB managed at a participating healthcare facility - people who are household contacts of TB cases managed at a participating healthcare facility Household contacts most at risk of tuberculosis are infants and children aged <5 years. They will be included in the study - that it, screened for TB disease and offered TB preventive therapy as per international and Indonesian guidelines. Their parents will be invited to participate in interviews about the experience of preventive therapy. Qualitative study: - consenting healthcare provider or key stakeholder involve in delivery of TB care - consenting TB patient or their parent / guiardian - consenting TB contact or their parent / guardian

Exclusion criteria

Nil

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026