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Anterior cruciate ligament reconstruction with the peroneous longus tendon

Patient outcome following peroneus longus autograft anterior cruciate ligament reconstruction in patients with anterior cruciate ligament rupture

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12618001454268
Acronym
PLA ACL reconstruction
Enrollment
30
Registered
2018-08-29
Start date
2018-09-03
Completion date
2018-12-31
Last updated
2018-09-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Several types of material are commonly used in anterior cruciate reconstruction (ACLR) with the majority of these coming from around the knee. Harvesting tendons may, however in itself cause pain and dysfunction. It is therefore desirable to identifly a harvesting method which does not lead to additional injury and possible dysfunction of the already injured knee while at the same time minimising such problems in other areas of the body. In recent years a small number of studies have been published regarding the use of peroneus longus (a tendon on the outside of the leg) autograft (PLA). These studies suggests PLA is a safe graft choice for ligament reconstruction and causes minimal dysfunction at the harvest site (the ankle). Our hypothesis is that PLA will perform as well as a hamstring tendon in ACLR while not causing pain and loss of strength in the knee nor significant dysfunction at the ankle . The project may potentially lead to the identification of peroneus longus as a suitable graft choice for ACLR. After the pilot study is completed we plan to conduct a randomised trial of peroneus longus versus standard graft (hamstring) to identify whether peroneus longus is superior to standard technique. These studies may lead to an improvement in the standard of care for patients with ACL rupture.

Interventions

Primary anterior cruciate ligament (ACL) reconstruction with a peroneus longus autograft. Instead of taking one of the hamstring tendons from behind the knee the peroneus longus tendon is taken from the outside of the ankle to make the new ACL. The whole operation takes approximately 40 minutes (around the same amount of time as a standard ACL operation using the hamstrings). All surgeries will be performed by Dr Kelly Macgroarty (FRACS orth) who is also the senior researcher.

Sponsors

Brisbane Knee and Shoulder Clinic
Lead SponsorOther Collaborative groups

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
16 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

Planned primary ACL reconstruction

Exclusion criteria

Revision ACL reconstruction Augmented ACL reconstruction Multiligament reconstruction Meniscal repair Previous foot or ankle surgery Chronic ankle instability Under 16 years of age Cannot read and understand english Unable to give consent

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026