None listed
Conditions
Brief summary
AIMS: This research project aims to collect information about the processes and outcomes of antibiotic allergy testing in a standardised way in order to improve future quality of care and outcomes for people with antibiotic allergies. The focus of this project will be on individuals with penicillin allergy labels. PARTICIPANTS: Patients who present to a hospital specialist service for assessment of penicillin allergy will be asked if they would like to participate. METHODS: Collection of information that will be routinely collected at the patient's routine penicillin allergy assessment visit and a follow up telephone call or email 8 weeks after the visit. An optional blood sample may be collected on the day to store for future research related to drug allergy. EXPECTED OUTCOMES: Improve access to antibiotic allergy delabelling services, improve the way in which appropriate advice after delabelling is provided to patients, and develop education resources for teaching and implementation of best practice into other nonhospital settings. This will provide safer and more cost effective care for all.
Interventions
Appropriate use of antibiotics is paramount in the era of multidrug resistant organisms and a dwindling new antibiotic pipeline. Data to guide the development of a safe, cost-effective and scalable antibiotic de-labelling strategy will improve health outcomes such as hospital length of stay, and reduce complications and costs associated with broad-spectrum antibiotics. We need to understand current practice, including variations in protocol, adherence to guidelines and resource requirements as a
Appropriate use of antibiotics is paramount in the era of multidrug resistant organisms and a dwindling new antibiotic pipeline. Data to guide the development of a safe, cost-effective and scalable antibiotic de-labelling strategy will improve health outcomes such as hospital length of stay, and reduce complications and costs associated with broad-spectrum antibiotics. We need to understand current practice, including variations in protocol, adherence to guidelines and resource requirements as a first step, then look to standardise prospective testing and de-labelling strategies. This observational, prospective study will be conducted in two phases. Phase 1 (months 1-5) will describe current antibiotic de-labelling practice at participating sites and the outcomes. Phase 2 (months 7-11) will compare the same endpoints as phase 1 after the implementation of an evidence-based, standardised antibiotic de-labelling protocol. It is anticipated that the standardised de-labelling protocol to be used in phase 2 of the study will be implemented following completion of this study.
Sponsors
St Vincent's Hospital, Sydney
Eligibility
Sex/Gender
All
Healthy volunteers
No
Inclusion criteria
Any patient who requires assessment of penicillin allergy. Willing and able to give written informed consent to participate in and comply with the study. (Or parent/guardian willing and able to give written informed consent if participant is a child). We have ethics approval to enrol paediatrics and adults
Exclusion criteria
Nil
Outcome results
None listed