None listed
Conditions
Brief summary
There is minimal evidence that the use of cardiac output monitor devices leads to an overall change in IV fluid use. We sought to investigate the feasibility of performing a randomised controlled study using calibrated cardiac output monitoring devices in shocked ICU patients and whether the use of these devices led to a difference in total volume of IV fluid administered.
Interventions
The intervention group will have 72 hours of monitoring following randomisation with an EV1000/VolumeView monitoring device. An EV1000/VolumeView system is a haemodynamic monitoring device which utlises transpulmonary thermodilution method to provide calibrated haemodynamic parameters to guide fluid resuscitation. To provide transpulmonary thermodilution, an internal jugular or subclavian central line and a femoral arterial line must be inserted to the study participant. ICU clinicians will be r
The intervention group will have 72 hours of monitoring following randomisation with an EV1000/VolumeView monitoring device. An EV1000/VolumeView system is a haemodynamic monitoring device which utlises transpulmonary thermodilution method to provide calibrated haemodynamic parameters to guide fluid resuscitation. To provide transpulmonary thermodilution, an internal jugular or subclavian central line and a femoral arterial line must be inserted to the study participant. ICU clinicians will be responsible for the placement of an internal jugular or subclavian central line and a femoral arterial line to fit the EV1000/VolumeView device. An EV1000/VolumeView provides constant haemodynamic parameters which require calibration by transpulmonary thermodilution every 4 hours. Nursing staff were responsible for calibration of the devices every 4 hours during the intervention period. Once the EV1000/VolumeView was established, there was no further active interventions for the interventional group or the control group.
Sponsors
Dr Timothy Scully
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
adult patients (18 years or older) admitted with shock defined as ongoing hypotension, despite fluid resuscitation, requiring vasopressors to maintain mean arterial blood pressure (MAP) greater than or equal to 65 mm Hg +/- and a serum lactate greater than or equal to 2 mmol/L.
Exclusion criteria
patients in hypovolemic/haemorrhagic shock or atrial fibrillation (AF), pre-existing need for dialysis, pregnancy and patients who were unlikely to remain in the ICU for at least 72 hours. Additionally, patients were excluded if advanced haemodynamic monitoring was consider essential by the treating clinician.
Outcome results
None listed