None listed
Conditions
Brief summary
Aim: To conduct a crossover longitudinal study to determine whether replacement of protein and fat from animal sources in Omnivore diet(OD) with same proportion of protein and fat from plant origin in Vegan diet ajusted (VDA) while maintain the overall energy intake has an effect on sleep pattern and their day-to-day sleep-wake cycle in healthy adults. Objectives: Primary: 1. To examine the effects of transition (acute or habitual) from OD to VDA and vice versa on sleep and 2. To examine the effects of exposure (post habitual) to VDA and OD and vice versa on sleep. Secondary: To examine the response measures associated with the sleep outcomes of OD and VDA diets. These measures include fasting blood glucose level, blood pressure, mood and alertness, and working memory.
Interventions
1. Description of the intervention; a. Omnivores Diet (OD): diet have the capability to obtain chemical energy and nutrients from materials originating from plant and animal. Often, omnivores also have the ability to incorporate food sources such as algae, fungi, and bacteria into their diet as well. b. Vegan Diet Adjusted (VDA): A vegan diet adjusted with the same proportion of protein and fat from plant origin as omnivores diet. 2. Duration of the base line period is two weeks and then we can get participants diet intake and sleep measurements before any input change occurs. 3. VDA is the same as OD with the same proportion of nutrients except difference in type of protein, CHO and fat (plant protein and fat vs animal protein and fat). 4. Participants will need to provide their own food and follow certain guidelines. 5. Within a healthy, balanced diet, a man needs around 10,500kJ (2,500kcal) a day and woman, that figure is around 8,400kJ (2,000kcal) a day. These values can vary depending on age, metabolism and levels of physical activity, among other things. these will be the same as the average daily kJ intake recorded during baseline period. 6. We have tried replacing the OD with VDA with similar levels of protein, fat, CHO and energy by weeks of trialling and producing numerous Vegan replacement diets (using Foodworks 9) that match the Omniovore diet in protein, fat, carbohydrate and energy proportions. To facilitate the menial, time-consuming (but important) task, we have now arrived at using a Calculator spreadsheet via a mathematical formulation (acknowledging Pemajayantha Vithanage, Mathematician) to find food combination of vegan foods to match nutrient values of the food people eat. This Calculator works well, with minor adjustments, in addition we use food diaries to record food intake by the participants. The study is to conduct. crossover longitudinal study of vegan diet vs animal diet using healthy adults(30) The crossover experiment study is designed in order to assess the effects of exposure to different diet regimen, plant origin diet (VDA) vs animal origin diet (OD), with the same proportion of nutrients except difference in type of protein, CHO and fat (plant protein and fat vs animal protein and fat), and the benefits or detriment of human sleep health as measured by sleep patterns and sleep-wake circadian rhythm, and the consequence of sleep outcomes including fasting blood glucose, mood and alertness, and cognitive functioning in working memory. The OD is participants’ normal mixed diet with meat, poultry, fish, eggs, dairy, vegetables, fruit and beverages. The VDA will be made with reference to the proportional dietary intake of OD. The Foodworks 9 nutrition software will be used to convert daily food intake into the nutritional components (protein, fat, carbohydrate, tryptophan, caffeine, zinc, alcohol, and sugar). OD during the baseline period will be used to calculate the portion of plant energy, CHO, protein and fat in VDA similar to the portion of animal protein and fat in OD. The serve sizes are taken from Australian dietary guidelines and recommended daily intakes from NHMRC and these sizes also will be used to calculate nutritional components.The experiment will be conducted at participants homes. The participants require to allocate their time only for 8 weeks. Eventhough this is a crossover trial no washout period because the study measure the effects of transition (acute or habitual) from OD to VDA and vice versa on sleep and the effects of exposure (post habitual) to VDA and OD and vice versa on sleep
Sponsors
Study design
Eligibility
Inclusion criteria
18 - 70 years and healthy
Exclusion criteria
People with mental illness: depression, bi-polar, schizophrenia, or sleep disorders: insomnia, periodic leg movements, sleep apnoea, narcolepsy, REM sleep behaviour disorder. Other major medical conditions (cardiovascular and respiratory diseases, anorexia nervosa, bulimia, metabolic syndrome), diabetes, who are on any medication, including herbal and vitamin that affect sleep. Participants who are pregnant or planning to become pregnant within next eight weeks, shift workers, vegans, people who consume =5 standard alcohol drinks on any day will be excluded from the study.