Airway oxygen concentration with high flow nasal oxygen

Airway oxygen concentration in patients undergoing airway surgery with high flow nasal oxygen as the primary oxygenation technique

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12618001256268

Enrollment

Registered

2018-07-25

Start date

2019-07-03

Completion date

2019-11-30

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is an observational study looking at patients undergoing airway surgery where High Flow Nasal Oxygen (HFNO) is used for patient oxygenation during a period of sustained apnoea. The study aims to characterise the change in oxygen (O2) concentration in the airway when O2 delivered by HFNO is decreased from 100% down to 30% This will enable us to objectively quantify oxygen levels at the surgical site when HFNO is being used to provide sustained apnoeic oxygenation As such it is anticipated that the study will represent a valuable contribution to patient safety by informing strategies that ensure safe and optimal surgical conditions during airway surgery in the presence of an ignition source.

Interventions

The group being observed is patients undergoing elective airway surgery with apnoeic oxygenation and high flow nasal oxygen (HFNO) as their primary oxygenation technique. The outcome or condition we are observing is the oxygen concentration in the airway, at the surgical site. The exposure is that delivered oxygen concentration (FiO2) will be decreased from 100% to 30% for 60 seconds.

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

Patients undergoing elective hypopharyngeal or laryngotracheal surgery where apnoeic oxygenation with High Flow Nasal Oxygen (HFNO) is the chosen anaesthetic technique Patients aged 18-75 years Patients deemed ASA 1-3

Exclusion criteria

Unable to give valid consent BMI >35 Not otherwise suitable for HFNO technique as deemed by anaesthetist ASA 4-5

Outcome results