Effects of Classic Coca cola enriched with and without vitamin C on metabolic status and oxidative stress in young men.

This study aimed to determine the metabolic effects and induction of oxidative stress related to consuming Coca cola in young men and to find out if adding vitamin C (ascorbate) can mitigate these effects. Methods: Oxidative stress markers (levels of total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI)), as well as metabolic parameters (IGF1 and IGFBP-3, fasting serum insulin and fasting serum glucose) in serum of healthy subjects will be determined. These results will be compared with the 15-day after the intervention. Subjects will be randomly assigned to two groups: 1: Classic Coca cola without vitamin C and 2: Classic Coca cola with 2 g vitamin C per liter (mixed in the beverage). The dose administered will be 2 liters daily in each group during 15 days. Patients will receive a two-liter container of the drink daily according to the group to which they belong. They will be informed that they can not take another different drink and the next day they will be given a new container replacing the empty container.