Betadine Sore Throat Gargle for removal of nasal Staphylococcus aureus

This study will have three treatment groups. Group 1 - Control (for nasal application) - 0.9% NaCl (sterile saline) - apply 1 soaked swab into each nostril for 30 seconds each, in two consecutive applications. At the end a total application time of 1 minute per nostril should be achieved. Repeat this twice a day (morning and evening), for total of 5 days. Group 2 - Mupirocin ointment cream (Bactroban ointment for nasal application) - Mupirocin 2% w/w active ingredient - approximately 0.5g into each nostril twice a day (morning and evening) for total of 5 days. Group 3 - Betadine Sore Throat Gargle (nasal application) - Povidone Iodine 7.5% w/v active ingredient - apply 1 soaked swab into each nostril for 30 seconds each, in two consecutive applications. At the end a total application time of 1 minute per nostril should be achieved. Betadine Sore Throat gargle is a single application (once only). This is a crossover trial. A washout period of 2 weeks will be provided to each participant before commencing the next treatment. Participants will be self administering the treatments. Participants will be provided with information of how the treatments should be applied. Compliance to treatment will be monitored by the return of used treatment vials and as part of the evaluation question at the end of treatment.