None listed
Conditions
Brief summary
Numerous studies on anti-plaque and anti-gingivitis agents provided strong evidence in favor of the use of antimicrobial agents such as mouthwashes as adjuncts to mechanical plaque control. Recently, essential oils containing mouthwashes have been demonstrated to be effective in reducing dental plaque and gingival inflammation. The present study was aimed to evaluate, after 3 months, the efficacy a newly-developed herbal mouthwash in patients suffering from moderate periodontal disease and to compare its efficacy to a placebo mouthwash.
Interventions
To assess the anti-inflammatory effect of a poly herbal mouthwash in periodontal patients after 3-month use and to compare it with placebo.
The mouthwash dose administered was 1ml diluted in a measuring cup (15ml) of water twice daily, for 1 minute
Participants adherence to the intervention was monitored by mouthwash bottle returns.
Sponsors
Istitutional funds from Prof. Putignano and Prof Orsini
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator)
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
Systemically healthy, minimum 20 teeth, smoker and no smoker, diagnosis of severe or moderate periodontitis
Exclusion criteria
Use of antibiotics and anti-inflammatory drugs in previous 6 months, presence of orthodontic appliance, pregnant or lactating females, allergy to the mouthwash ingredients
Outcome results
None listed