None listed
Conditions
Brief summary
12 patients in the Auckland Heart Transplant programme will be invited to participate in a study to measure the gene and protein levels of various hormones in the heart and blood. These hormones are important in controlling blood pressure and the load placed upon the heart. We are investigating which hormones are potentially important in the development of heart problems. Measurements of these hormones could potentially be useful for clinical disease diagnosis and outcome. Participants will be asked to give consent for the use of their heart tissue and blood for this study. They will be asked to complete a questionnaire about their health and demographic details. Blood samples (20ml volume) will be taken at the time of the transplant surgery. We also require 10grams of tissue from each of the atrium and ventricle chambers of the heart. This will be taken from the heart removed at the time of surgery. The process of taking this tissue will in no way compromise the safety and procedure of surgery or affect standard clinical care.
Interventions
12 patients in the Auckland Heart Transplant programme will be invited to participate in a study to measure the gene and protein levels of various hormones in the heart and blood. Participants will be asked to complete a questionnaire about their past medical history, medications, social history (tobacco and alcohol use) and demographic details (age, sex, ethnic group). Blood samples (20ml volume) will be taken at the time of transplant surgery. Participants are not followed up after completion
12 patients in the Auckland Heart Transplant programme will be invited to participate in a study to measure the gene and protein levels of various hormones in the heart and blood. Participants will be asked to complete a questionnaire about their past medical history, medications, social history (tobacco and alcohol use) and demographic details (age, sex, ethnic group). Blood samples (20ml volume) will be taken at the time of transplant surgery. Participants are not followed up after completion of transplant surgery. We also require 10grams of tissue from each of the atrium and ventricle chambers of the explanted heart.
Sponsors
The Christchurch Heart Institute Trust
Eligibility
Sex/Gender
All
Age
18 Years to 63 Years
Healthy volunteers
No
Inclusion criteria
All participants on the cardiac transplant waiting list aged 18-63 will be invited to participate.
Exclusion criteria
unable or unwilling to participate
Outcome results
None listed