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Office-based Program To Improve Metabolic control In Sedentary Employees with type 2 diabetes: The ‘OPTIMISE Your Health' study

Reducing sitting time on glycaemic control in middle-aged and older office workers with type 2 diabetes

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12618001159246
Acronym
OPTIMISE
Enrollment
126
Registered
2018-07-13
Start date
2019-06-03
Completion date
2024-04-30
Last updated
2026-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Approximately 250 volunteers will be required for this study. The study will test whether a 6-month multicomponent intervention (involving health coaching, sit-stand workstations at work, and a smartphone behavioural promoting tool) can reduce daily sitting time and improve blood glucose control as well as risk markers for cardiovascular disease (blood pressure and blood vessel health). The results of this trial will build on our understanding of the cardiometabolic consequences (i.e. high risk of developing heart disease) of too much sitting in individuals with type 2 diabetes and will help design intervention strategies in the community to reduce the risk of developing complications associated with diabetes.

Interventions

This is an 18-month, controlled-trial design, in which middle-aged and older office workers with T2D (n=250) will be randomly assigned to one of two conditions: 1) a multi-component intervention to reduce sitting time; 2) a usual-care control condition. Those randomised to the multi-component intervention will receive the following: • Health coaching: Trained-researchers in motivational training will deliver the health coaching sessions. The health coaching sessions will consist of two in-person

This is an 18-month, controlled-trial design, in which middle-aged and older office workers with T2D (n=250) will be randomly assigned to one of two conditions: 1) a multi-component intervention to reduce sitting time; 2) a usual-care control condition. Those randomised to the multi-component intervention will receive the following: • Health coaching: Trained-researchers in motivational training will deliver the health coaching sessions. The health coaching sessions will consist of two in-person meetings and eight telephone-delivered sessions over six months, to support initiation and maintenance of the sitting-time reduction changes. Both the face to face and telephone health coaching sessions will focus on delivering two key messages: Sit less and move more, both at work and outside of work. the following 6-months will consist of text message support via the propelo system. The in-person meetings will occur at baseline (at the participant’s workplace) and at the three month assessment (at Baker Institute) and will include the following: provision of feedback on baseline levels of sitting time, assessment and strategies to enhance motivation, and identify/set goals related to reducing and breaking-up sitting time in both the home and work environment. A participant workbook will also be provided to participants to help with goal setting and progress. The telephone calls will be brief (~10min) and used to check on progress on reducing sitting at home and at work, address problems, revise goals as needed and reinforce goal attainment. The telephone calls will be once a week for the first three weeks and then every three weeks until the end of the intervention. • Sit–stand desktop workstations: A manually adjustable sit–stand workstation will be provided for the duration of the study to use at the participant’s workplace. All participants will be required to provide written approval from their employer to use the workstation in the workplace. During the intervention, participants will be encourage to use the sit-stand workstation throughout their whole work day by regularly alternating between sitting and standing throughout the work day. After the intervention, participants will retain the sit-stand workstation. • Smartphone-based monitoring and behavioural prompting: A wrist-worn activity monitor (Fitbit) and Fitbit mobile app will be provided to each participant to continuously self-monitor their daily movement patterns in real-time over the 18 month intervention. On the smartphone app, participants can set prompts to interrupt their idle states and also receive reinforcing feedback in real-time on interruptions to prolonged periods of sedentary behaviour. Research staff will set up the Fitbit watch and the app during the initial face-to-face intervention session and encourage participants to use the device. The intervention group’s outcomes will be compared at three, six, twelve and eighteen months to those of the control condition.

Sponsors

Baker Heart and Diabetes Institute
Lead SponsorOther

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Investigator)

Eligibility

Sex/Gender
All
Age
35 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

• Aged between 35-65 years; • Have a body mass index (BMI) between 25-50 kg/m2; • Be medically diagnosed with T2D for at least three months • T2D to be treated by diet alone or with oral hypoglycaemic agents or GLP1 agonists and be on stable treatment regimen for > 3 months • Stable body weight (+/-5 kg) for > 3 months prior to beginning the intervention • Working at least 0.8 full-time equivalent in a desk-based occupation for > 6 months with the same employer and able to obtain employer permission to install the provided sit–stand workstation on their work surface. • Working in the Melbourne metropolitan area within a 40km radius from Baker Clinic

Exclusion criteria

• Using insulin to treat T2D • HbA1c less than 6.5% (indicative of good control) or greater than 10% (reflects uncontrolled); • Pregnant • Women of childbearing potential not currently using adequate contraception • Non-Smartphone user • Currently using a height adjustable workstation at their workplace • Regularly engaged in moderate-vigorous intensity exercise more than 30 min/day for more than 3 months • Regularly engaged in more than 30 minutes/week of structured strength/resistance training (i.e. involving machine or free weights) for more than 3 months • Regularly sits for less than 7 hours per day for more than 3 months • Major illness/physical problems (acute or chronic) that may limit participation in the intervention. • Significant cardiovascular disease (unstable angina, cardiac failure) or recent myocardial infarction, coronary artery bypass graft, ischaemic or haemorrhagic stroke in the previous 3 months • Cancer diagnosis in the previous 12 months • A medically diagnosed and untreated severe sleeping disorder • Planning to move from the current employer in the next 6 months • Intending to have an extended vacation (greater than 4 weeks) in the next 6 months • Unable to communicate in English • Unable to provide written informed consent

Outcome results

None listed

Source: ANZCTR · Data processed: Sep 19, 2026