None listed
Conditions
Brief summary
The primary objectives will be to assess the effects of trifle sweetened with different sugars on satiety and day-long energy intakes. The sugars will induce different glycaemic responses in the participants. The study hypothesis is that a more stable blood glucose concentration over time, represented by the isomaltulose treatment, will result in greater satiety. The study will have a crossover design in which each participant will consume an isomaltulose and a sucrose sweetened trifle in randomized order. Participants will attend two laboratory sessions separated by two weeks. On the day before each test day, participants will be given a standardized individually boxed ready-to-eat breakfast cereal to consume on the morning of the test. The test will run from 12 noon to 5pm. A baseline blood sample collected via fingerprick will be taken. Following consumption of the trifle, satiety will be assessed using four questions with feelings of satiety recorded using validated visual analogue scales. The set of four questions will be asked at baseline and at 30, 60, 90, 120 and 150 minutes after eating the trifles. Capillary blood for testing blood glucose concentration will be taken via fingerprick at 60 and 120 minutes after baseline. Weighed diet records will be taken throughout each test day. Data analysis will be undertaken by a biostatistician blinded to treatment.
Interventions
This will be a double-blind crossover trial in which 77 healthy adults will eat trifle for lunch containing either 73g of sucrose or isomaltulose. The order in which participants receive the trifles will be randomised to each person. There will be a 2 week washout between test days. After an overnight fast of 8h, on the mornings of the test days, participants will be provided with the same breakfast cereal to standardise the mormings food intake. The breakfast will be consumed at a time conveni
This will be a double-blind crossover trial in which 77 healthy adults will eat trifle for lunch containing either 73g of sucrose or isomaltulose. The order in which participants receive the trifles will be randomised to each person. There will be a 2 week washout between test days. After an overnight fast of 8h, on the mornings of the test days, participants will be provided with the same breakfast cereal to standardise the mormings food intake. The breakfast will be consumed at a time convenient to the participant, but at the same time on both test days. Between finishing breakfast and lunchtime, participants will be asked to abstain from food and drink, apart from water. At 12pm, participants will eat 446g of trifle within 15 minutes. Eating lunch and assessment of satiety questions will be under the supervision of the study investigators. Participants will record food and beverage intake throughout each test day (midnight to midnight)
Sponsors
University of Otago
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy adults
Exclusion criteria
Food allergies to any of the trifle ingredients
Outcome results
None listed