None listed
Conditions
Brief summary
Aim: To determine if outpatient management (via Hospital in the Home [HITH]) of uncomplicated acute diverticular disease is as safe and effective. Research Design: Patients who present to University Hospital Geelong Emergency Department diagnosed with acute uncomplicated diverticulitis with be randomised into either an intravenous antibiotics group or oral antibiotic group. Both groups will be treated as outpatients with the Hospital in the Home team. Primary Endpoint: Time to resumption of normal activities of daily living. Secondary Endpoints: Pain, Diet, Bowel habit, Patient satisfaction, Biochemical markers, Cost comparison.
Interventions
Treatment of patients as outpatients under the care of the Hospital in the Home (HITH) team. Groups will be treated in one of two treatment arms, either with intravenous antibiotics or oral antibiotics.
IV antibiotics: Ceftriaxone 1g once daily, Metronidazole 500mg twice daily. (Three days total)
Oral antibiotics: Augmenting Du Forte 875mg/125mg twice daily. (Five days total).
Visits by HITH team members to ensure compliance.
Sponsors
Dept of Surgery - Barwon Health
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
CT proven uncomplicated acute diverticulitis. Observation for two hours without deterioration. Eligible for HITH.
Exclusion criteria
Active co-mobidities (i.e. Diabetes, Heart failure, Kidney failure). Lives alone/poor social supports. Clinical deterioration in first two hours of observation. Unwilling to be treated at home with HITH.
Outcome results
None listed