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An Australia and New Zealand-wide survey of extracorporeal membrane oxygen (ECMO)-related infection and dressing and securement practices.

An Australia and New Zealand-wide point prevalence study to determine extracorporeal membrane oxygenation (ECMO)-related infection rates and cannulae dressing and securement practices.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12618001109291
Enrollment
127
Registered
2018-07-04
Start date
2017-09-26
Completion date
2018-08-26
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This project is a point prevalence study of ECMO-related infection and cannula dressing and securement practices in both adult and paediatric populations across Australia and New Zealand. The aims of this project are to identify the following: (1) Prevalence of ECMO cannulation site infection (local infection) (2) Prevalence of ECMO-related bloodstream infection and other nosocomial infections (3) ECMO cannula dressing and securement practices, and adherence to local dressing/securement guidelines Data will be collected on each eligible patient on one day during the pre-specified data collection week. There will be one data collection week per month for 12 months. It is hypothesised that this data will give an accurate snapshot of the prevalence of nosocomial infections and of cannula dressing and securement practices across Australia and New Zealand in patients receiving ECMO.

Interventions

Extracorporeal membrane oxygenation (ECMO) is an invasive mechanical therapy used to provide cardio-respiratory support to critically ill patients when maximal conventional support has failed. Nosocomial infection is one of the most frequent and serious complications of ECMO and is reported in up to 64% of patients. It leads to longer periods of mechanical ventilation and ECMO support, as well as longer hospital stays and increased mortality. ECMO is delivered via large-bore cannulas, which must

Extracorporeal membrane oxygenation (ECMO) is an invasive mechanical therapy used to provide cardio-respiratory support to critically ill patients when maximal conventional support has failed. Nosocomial infection is one of the most frequent and serious complications of ECMO and is reported in up to 64% of patients. It leads to longer periods of mechanical ventilation and ECMO support, as well as longer hospital stays and increased mortality. ECMO is delivered via large-bore cannulas, which must be adequately secured both at the insertion site and along the length of the cannula to avoid complications such as cannula migration, dislodgement and local and systemic infection. This point prevalence study will be a one week, observational study conducted over twelve separate weeks. Each study week will be separated by approximately one calendar month. On each study week, all sites will collect data for each eligible ECMO patient.

Sponsors

The Prince Charles Hospital
Lead SponsorHospital

Eligibility

Sex/Gender
All
Healthy volunteers
No

Inclusion criteria

(1) Patients undergoing ECMO treatment with a circuit that includes a membrane oxygenator and pump (2) Patients decannulated from ECMO <48 hours prior to data collection days

Exclusion criteria

(1) Patients who have already had data captured on a previous data collection day (2) Patients decannulated from ECMO for > 48 hours on data collection days (3) ECMO circuit does not include a membrane oxygenator and pump

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026