None listed
Conditions
Brief summary
Pre-operative anaemia, as defined by the World Health Organisation criteria, has a prevalence in non-cardiac surgery of around 25% and is associated with poorer outcomes peri-operatively. It also increases the chance of transfusion and increases risk of death in cardiac surgery. Blood transfusion is often used to correct peri-operative anaemia and whilst life saving in acute major haemorrhage is a limited resource and, is itself associated with morbidity and mortality. It remains unclear if treating anaemia in the peri-operative period can positively influence morbidity or mortality. However benefit from patient blood management interventions, including pre-operative anaemia optimisation, has been shown to reduce the need for blood transfusion with possible trends towards improved patient outcomes. Guidelines have been published recommending identification and active management of preoperative anaemia. An excellent goal directed review has been undertaken by the Australian National Blood Authority and also supports identification and optimisation of pre-operative anaemia. A preliminary look reviewing colorectal patients over a six month period in 2017 was recently undertaken at St George. Of the 171 elective operative cases found, ninety had a preoperative haemoglobin reported thirty of which were anaemic (33% of those who had a haemoglobin). Eight patients were transfused during the peri-operative period, the majority of whom were anaemic before surgery. This pilot study supports the published literature, and implies the problem of pre-operative anaemia is present at St George and currently insufficiently managed. Pre-operative anaemia may be an optimisable risk factor for our patients at St. George, first however we need to understand which patient groups are at greatest risk, their current management (blood product transfusions) and then how and where to focus our efforts. This work has not been previously undertaken at St George. The primary aim of the proposed study is to document the prevalence of anaemia pre-operatively and transfusion practice for all patients having a procedure in 2017 at St George Hospital. Secondary aims include the documentation of anaemia according to surgical speciality, of pre-operative iron deficiency anaemia, anaemia of chronic disease and of blood product transfusions according to patient demographics and surgical speciality. The study will also examine the timings from booking to surgery and pre-operative assessment to surgery to consider how best to optimise Haemoglobin (Hb) during the patients pre-operative pathway.
Interventions
We will be investigating the presence of anaemia in surgical patients, within 2 months prior to surgery up to the date of their surgery. Anaemia will be defined by a Hb less than 120g/L in females and less than 130g/L in males. We will also be investigating the prevalance of iron deficient anaemia, within 2 months prior to surgery. Iron deficiency anaemia will be defined as anaemia with ferritin level less than 30mcg/L, or ferritin level less than 100mcg/L and Transferrin Saturation (TSats) less than 16%, we will be investigating the presence of anaemia in surgical patients within 2 months of their surgery. We will also be investigating the prevalance of anaemia of chronic disease, within 2 months prior to surgery. Anaemia of chronic disease is defined as anaemia with ferritin greater than 100mcg/L and TSats greater than 16%
Sponsors
Eligibility
Inclusion criteria
All surgical procedures performed at St George Hospital during 2017 in patients 16 years or older.
Exclusion criteria
All those undergoing a surgical procedure at St George Hospital under the age of 16 years.