inflammatory markers of lining of womb in infertile women with dilated fallopian tube

Endometrial inflammatory markers in infertile women with hydrosalpinx

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12618001003268

Enrollment

Registered

2018-06-14

Start date

2018-10-01

Completion date

2019-10-30

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

It is possible that the deleterious effect of hydrosalpinx fluid may not be limited to direct embryotoxicity, and may, in fact, be the result of an induced inflammatory response within the endometrial cavity. By evaluating inflammatory mediators and by analyzing the number and type of infammatory cells in the endometrium of patients with hydrosalpinges, we aim to determine whether there is an endometrial contribution to the compromised reproductive outcome in those patients.

Interventions

Infertile women exposed to inflammation of fallopian tube causes inflammation of endometrium and causes failure of implantation and inability to conceive for at least 2 years ,women enrolled in study will investigated on admission by laboratory , histopathology and immunohistochemistry examination of endometrial biopsy done under general anesthesia .

Eligibility

Sex/Gender

All

Age

25 Years to 35 Years

Healthy volunteers

Inclusion criteria

Primary or secondary infertility due to tubal factor

Exclusion criteria

Infertility due to unknown reasons other than salpingitis,Female with one of the following endocrine abnormalities: polycystic ovary or hyperprolactinemia.Female presenting abnormal cervical cytological examination: HPV infection or atypical cell hyperplasia or more.Acute inflammation of the genital tract.

Outcome results