None listed
Conditions
Brief summary
Objectives: (1) to identify the influence of aerobic exercise on prostaglandin (PGF2, PGE2, TXB2) levels in blood plasma of women with primary dysmenorrhea (2) to evaluate the effects of aerobic exercise on pain in women with primary dysmenorrhea. Recruitment: Advertising will be done by posting study flyers around the University campus, waiting rooms of the PolyU University Health. The advertisement flyers will contain simple inclusion information as well as contact details of the principal investigator. Exercise group: Women in the exercise group will perform supervised treadmill-based aerobic exercise at a perceived exertion of 11.0 (Borg RPE) for the first five minutes (warm-up period), followed by aerobic exercise at 70-85% of MHR (16-18.0 Borg scale) for 25 minutes. At the end of the exercise session women will complete a 5-minute cool down (11.0 Borg scale). No-exercise group: will not be provided study intervention. Participants will only be required to provide blood samples for estimation of prostaglandin levels and complete pain questionnaire. Outcomes assessment time points: Collection of blood samples and measurement of pain intensity will be done on the first day of the first menstrual period following entry into study to establish baseline (pre-intervention; Month 0) plasma variables and pain intensity levels. Post-intervention assessment will during the second menstrual period. Study outcomes will be assessed on the day of maximum pain and bleeding which is usually the second day of menstrual period.
Interventions
Supervised treadmill-based aerobic exercise at a perceived exertion of 11.0 (Borg RPE) for the first five minutes (warm-up period), followed by aerobic exercise at 70-85% of MHR (16-18.0 Borg scale) for 25 minutes. At the end of the exercise session, women will complete a 5-minute cooldown (11.0 Borg scale).
Exercise intervention will be done three times a week for up to 4 weeks.
The intervention will be supervised on a one-to-one basis by a physiotherapist with specialist experience in Women'
Supervised treadmill-based aerobic exercise at a perceived exertion of 11.0 (Borg RPE) for the first five minutes (warm-up period), followed by aerobic exercise at 70-85% of MHR (16-18.0 Borg scale) for 25 minutes. At the end of the exercise session, women will complete a 5-minute cooldown (11.0 Borg scale). Exercise intervention will be done three times a week for up to 4 weeks. The intervention will be supervised on a one-to-one basis by a physiotherapist with specialist experience in Women's health.Adherence to experimental intervention will be monitored by the study personnel. While participants are on the treadmill, the following data will be monitored every five minutes: (1) heart rate (HR) with a HR monitor (2) rate of perceived exertion using Borg’s 6-20 scale. The intervention will be provided at the Department of Rehabilitation Sciences, the Hong Kong Polytechnic University.
Sponsors
Priya Kannan
Study design
Allocation
Non-randomised trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
18 Years to 29 Years
Healthy volunteers
No
Inclusion criteria
Non-pregnant women in the age group 18-29 years, with regular menstrual cycles, and menstrual pain equivalent to or greater than 4 on a 0-10 Visual Analogue Scale (VAS) will be considered eligible to participate in the study
Exclusion criteria
Pregnant women, women having menstrual pain less than 4 out of 10 on visual analogue scale, women on formal exercise programme
Outcome results
None listed