None listed
Conditions
Brief summary
Laparascopic surgical interventions are gaining popularity, but the induction of pneumoperitoneum has been seen alterations in the respiratory mechanics.. These alterations are known to result in a reduction in FRC, VC, an increase in PaCO2, hypoxemia, ventilation / perfusion incompatibility. This issue has revealed the positive effects of administration of positive end expiratory pressure (PEEP) on elastance and resistance in the respiratory system. However, there are publications showing that PEEP application enhances ICP. Pneumoperitoneum also increase in ICP at any given time. The optic nerve sheath continues with the duramater, and a change in the CSF pressure at the subarachnoid location affects the diameter of the optic nerve sheath. In this study, we aimed to control 10 cmH2O PEEP in ICP change in 15 mm Hg pneumoperitoneum patients by the change of the optic nerve sheath diameter (Optic nevre sheet diamaetr is measured by ultrasound).
Interventions
PEEP was implemented by an anesthesia assistant who was not included in the study and anesthesia researcher who does not know whether the patient is peeping or not peeping, measured optic nerve sheath diameter by ultrasound.
Group Peep: 10 cm H2O Peep administered during the operation (about one hour)
Group zero PEEP: no PEEP administered during the operation
The effect of 10 cm H2O PEEP on optic nerve sheet diameters measured by ultrasound
t1 = Before anesthesia induction
t2 = After entubatio
PEEP was implemented by an anesthesia assistant who was not included in the study and anesthesia researcher who does not know whether the patient is peeping or not peeping, measured optic nerve sheath diameter by ultrasound. Group Peep: 10 cm H2O Peep administered during the operation (about one hour) Group zero PEEP: no PEEP administered during the operation The effect of 10 cm H2O PEEP on optic nerve sheet diameters measured by ultrasound t1 = Before anesthesia induction t2 = After entubation t3 = Following pneumoperitoneum administration t4 = After PEEP administration t5 = After desuflation t6 = Following extubation Also, heart rate, mean arterial pressure, peak airway pressure, platau pressure were recorded at the same times
Sponsors
Diskapi Yildirim Beyazit Education and Research Hospital
Study design
Allocation
Randomised controlled trial
Primary purpose
Prevention
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
ASA I-II who were scheduled to undergo laparascopic cholecystectomy.
Exclusion criteria
Presence of acute/chronic Eye disease, Hypertension,Pulmonary disease,Obesity
Outcome results
None listed