None listed
Conditions
Brief summary
Purpose: Our aim was to assess changes in the total retinal thickness (TRT), total retinal volume (TRV) and retinal layer thickness after uncomplicated cataract surgery. Methods: A total of 32 eyes of 32 patients who had undergone uncomplicated phacoemulsification surgery and intraocular lens implantation in one eye were enrolled. Effective phacoemulsification time (EPT) and total energy (TE) were recorded. Thickness and TRV were measured using optical coherence tomography. Data were collected preoperatively and at postoperative day 1, 7, 30, 90 and 180. Results: The study results showed a decrease in TRT, TRV and most retinal layer thicknesses at the first postoperative day visit, then increasing at week 1, month 1 and 3, and then relatively decreasing at month 6 although not returning to preoperative levels. The least affected layers were the retinal pigment epithelium and outer plexiform layer. There was a positive correlation between EPT and TE and ganglion cell layer in a 1 mm circle and inner nuclear layer in a 1-3 mm circle (p<0.05). Conclusion: The results suggest that long-term follow-up of more than 6 months is necessary after cataract surgery to see if total retinal and segmental values return to preoperative levels.
Interventions
Cataract surgery was performed with the Infiniti phacoemulsification device. After surgery, the changes of retinal layer thicknesses were evaluated by spectral domain optical coherence tomography. The image acquisition was followed by automatic intra-retinal layer segmentation performed by the inbuilt Spectralis software. Intra-retinal layer thicknesses were obtained for each Early Treatment Diabetic Retinopathy Study subfield at a central 1 mm circle and 1-3 mm circles. The cataract surgery wou
Cataract surgery was performed with the Infiniti phacoemulsification device. After surgery, the changes of retinal layer thicknesses were evaluated by spectral domain optical coherence tomography. The image acquisition was followed by automatic intra-retinal layer segmentation performed by the inbuilt Spectralis software. Intra-retinal layer thicknesses were obtained for each Early Treatment Diabetic Retinopathy Study subfield at a central 1 mm circle and 1-3 mm circles. The cataract surgery would be performed regardless of whether the participants are enrolled in the study. Data were collected preoperatively, and on postoperative day 1, 7 (first week), 30 (first month), 90 (third month) and 180 (sixth month).
Sponsors
Ahi Evran University Training and Research Hospital
Eligibility
Sex/Gender
All
Age
48 Years to 79 Years
Healthy volunteers
No
Inclusion criteria
Patients undergoing phacoemulsification surgery with intraocular lens implantation. Be at least 45 years old, male or female. Willing to measure retinal layer thickness before and after cataract surgery.
Exclusion criteria
macular pathologies, retinal vascular occlusion, history of any other ocular disorder (including uveitis, severe dry eye, eye trauma, glaucoma, pseudoexfoliation syndrome) or surgery, any systemic disorder (such as diabetes, hypertension, asthma or chronic obstructive pulmonary disease), systemic inflammation (inflammatory bowel disease, hepatitis B or C), the current use of any topical or systemic medication or anti-inflammatory agent, intraoperative complications such as posterior capsular rupture, vitreous loss, iris prolapse and low scan quality images due to dense cataract.
Outcome results
None listed