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Delayed fetal cord clamping in preterm labour, Risk and benefits

Delayed fetal cord clamping in premature labour: the effect on fetal haemoglobin, bilirubin and neonatal death, maternal haemoglobin, neonatal ICU admission and postpartum haemorrhage,

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12618000758202
Enrollment
210
Registered
2018-05-07
Start date
2018-10-01
Completion date
2019-06-01
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Preterm birth is a major cause of death and a significant cause of long-term loss of human potential all around the world. Complications of preterm birth are the single largest direct cause of neonatal deaths and the second most common cause of under-5 deaths after pneumonia..All newborns are generally fragile and more so premature babies, making them in continuous need for special care . Advances in medical technology have contributed to smaller infants surviving past the neonatal period. This survival,however, is fraught by many complications including respiratory distress syndrome , neonatal indirect hyperbilirubinemia , sepsis, apnea and anemia of prematurity .Our study hypotheses that delayed clamping in preterm labor allows time for transfusion of placental blood to the newborn infant. This can provide the neonate with an additional blood volume,decrease need for blood transfusion as reported by American congress of obstetricians and gynecologists thereby protecting it from anemia.

Interventions

Arm 1 will be subjected after fetal body expulsion to immediate(first 5 seconds) cord clamping between two clamps without cord milking in neonates delivered prematurely at 30 to 34 weeks gestation. by obstetrician attending the labour, and recorded in the patient file. duration of intervention <5 seconds.

Sponsors

Alzhraa university hospital
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
19 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

women who delivered prematurely at 30 - 34 weeks gestation, singleton, delivered either normal vaginal or cesarean section.

Exclusion criteria

Maternal medical disorder ( diabetes , hypertension ) Fetal congenital anomalies Meconium stained amniotic fluid Placenta previa , abruption

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026