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Effects of isothermic coloading with crystalloids during spinal anesthesia for cesarean delivery on maternal vital signs and fetal outcomes

Effects of isothermic coloading with crystalloids during spinal anesthesia for cesarean delivery on maternal vital signs and fetal outcomes

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12618000739213
Acronym
none
Enrollment
60
Registered
2018-05-03
Start date
2018-06-01
Completion date
2018-07-17
Last updated
2018-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

hypotension is a common occurance in parturients undergoing cesarean section with spinal anesthesia. several modalities have been tested to prevent or decrease the degree of hypotension in paturients during cesarean section under spinal anesthesia. In the recent studies, coloading with crystalloids is reported to be superior than preloading with crystalloids. The current study is conducted to determine the effect of isothermic coloading with crystalloid fluid on maternal vital signs and fetal apgar scores.

Interventions

pregnant patients undergoing cesarean section under spinal anesthesia will be randomly allocated into two groups. Control group will be hydrated with single dose 15ml/kg of intravenous crystalloid solution at room temperature and study group will be hydrated with single dose 15ml/kg of intravenous crystalloid solution at body temperature (37 degrees celsius) by the anesthesia nurse of the operation room following administration of spinal anesthesia (following the removal of spinal needle in 5 m

pregnant patients undergoing cesarean section under spinal anesthesia will be randomly allocated into two groups. Control group will be hydrated with single dose 15ml/kg of intravenous crystalloid solution at room temperature and study group will be hydrated with single dose 15ml/kg of intravenous crystalloid solution at body temperature (37 degrees celsius) by the anesthesia nurse of the operation room following administration of spinal anesthesia (following the removal of spinal needle in 5 minutes). The temperature of the infusion fluid will be kept constant using a warming device.

Sponsors

mehmet canturk
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

parturients scheduled for elective cesarean section under spinal anesthesia with term singleton uncomplicated pregnancies.

Exclusion criteria

parturients that reject spinal anesthesia or that have any contraindication for spinal anesthesia. Parturients that refuse to be involved in the study. Complicated pregnancies or any history of fetal abnormalities. Emergency cases.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026