None listed
Conditions
Brief summary
Fluid management usually relies on increasing preload to augment cardiac output in critically ill patients. However, recent studies have failed to demonstrate the anticipated effect in approximately 50% of the patients.This has resulted in a need for developing an accurate and reliably technique to guide the fluid management. Current preload variables such as central venous pressure (CVP) and pulmonary capillary wedge pressure (PCWP) are not reliable variables to manage fluid resuscitation. On the other hand, volumetric preload variables assessed with transpulmonary thermodilution may be superior in reflecting the left ventricular preload; however, these variables do not allow the evaluation of the fluid responsiveness. As a less invasive hemodynamic monitoring system based on arterial pulse contour analysis, stroke volume variation (SVV) allows continuous monitorization of the fluid status, and several studies have suggested that CVP can be reliably replaced by SVV in the management of fluid therapy. In the present study, therefore, we aim to evaluate whether SVV can guide fluid therapy in thoracic surgery and reduce complications.
Interventions
Group 1 (Stroke volume variation (SVV) group): The FloTrac Device (Vigileo TM Edwards Lifesciences, LLC, Irvine, CA, USA) was connected to the arterial line. The SVV measurements were taken into consideration, when tidal volume was 8 mL/kg and the thorax was closed (SVV variables were collected from intubation to skin incision and from the closure of the thorax until the end of surgery). All patients were treated with 500 mL crystalloid fluid loading intravenous infusion at the first hour. Maint
Group 1 (Stroke volume variation (SVV) group): The FloTrac Device (Vigileo TM Edwards Lifesciences, LLC, Irvine, CA, USA) was connected to the arterial line. The SVV measurements were taken into consideration, when tidal volume was 8 mL/kg and the thorax was closed (SVV variables were collected from intubation to skin incision and from the closure of the thorax until the end of surgery). All patients were treated with 500 mL crystalloid fluid loading intravenous infusion at the first hour. Maintenance fluid therapy was given in the intravenous boluses of 2 mL/kg, if the SVV value was greater than or equal to 13%. After the first 1000 cc crystalloid intravenous infusion treatment was added to the colloid.
Sponsors
Cengiz Sahutoglu
Study design
Allocation
Non-randomised trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
Patients undergoing lobectomy
Exclusion criteria
Patients undergoing surgical procedures other than lobectomy those with severe valvular disease and arrhythmia respiratory function test results below 50% severe organ failure (kidney, liver, and heart failure) patients without epidural catheter pediatric cases
Outcome results
None listed