None listed
Conditions
Brief summary
Our aim is to assess whether ultrasound-guided subcostal oblique transversus abdominis plane (OSTAP) block would improve the postoperative pain scores and decrease the tramadol consumption after laparoscopic hysterectomy. Female patients between ages 18 and 65 years, with ASA I to III, undergoing elective total laparoscopic hysterectomy will be included in the study. Patients will be randomized into 2 groups. In group OSTAP, patients will receive bilateral OSTAP block and tramadol patient-controlled analgesia (PCA) IV for the first postoperative 24 hours. Patients in group no-TAP will receive an US-guided bilateral OSTAP with 40 ml 0.9% saline. They will receive the same tramadol PCA. The primary outcome measure of the study will be the 24-hour tramadol consumption. The secondary outcome measures of the study includes VAS scores and 1st, 4th and 12th hour tramadol consumptions.
Interventions
In this study we are using an ultrasound procedure for transversus abdominis plane block for patients undergoing laparoscopic hysterectomy. After induction and intubation before the initiation of surgery OSTAP blocks will be performed under ultrasonography guidance using a linear 6 to 13 MHz ultrasound probe by the anesthesist. In group OSTAP patients will receive an ultrasound (US)-guided bilateral OSTAP block with 40 mL of 0.375% bupivacaine and tramadol patient-controlled analgesia (PCA) IV
In this study we are using an ultrasound procedure for transversus abdominis plane block for patients undergoing laparoscopic hysterectomy. After induction and intubation before the initiation of surgery OSTAP blocks will be performed under ultrasonography guidance using a linear 6 to 13 MHz ultrasound probe by the anesthesist. In group OSTAP patients will receive an ultrasound (US)-guided bilateral OSTAP block with 40 mL of 0.375% bupivacaine and tramadol patient-controlled analgesia (PCA) IV. The severity of pain according to visual analogue scale (VAS), total and cumulative tramadol consumption, incidence of nausea and vomiting will be assessed by the blind anesthesiologist who performed the block.
Sponsors
MELIKE KORKMAZ TOKER
Study design
Allocation
Randomised controlled trial
Primary purpose
Treatment
Masking
Blinded (masking used) (Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
Patients aged between 18 and 65 years, with ASA physical status I to III, undergoing elective total laparoscopic hysterectomy will be included to the study.
Exclusion criteria
Patients with a history of chronic opioid therapy in the 6 months before surgery, conversion to open surgical technique, aspartate aminotransferase and/or alanine aminotransferase >250 IU, creatinine level >1.4 mg/dL, pregnancy or lactation, known allergy to any drug used in the study, local infection at the block site and opioid abuse will be excluded from study.
Outcome results
None listed