None listed
Conditions
Brief summary
Hemodynamic changes can be seen during induction of general anaesthesia. Especially hypotension occurs. Althought there are several factors in determining the perfusion of cerebral tissue, the most important one is mean arterial blood pressure. In a study performed, cerebral tissue oxygen saturation was evaluated after induction of anaesthesia and there was no change in cerebral tissue oxygen saturation despite hypotension in patients. Cerebral tissue perfusion can be maintained at a constant current due to autoregulation against changes in mean arterial pressure. However, cerebral tissue perfusion in hypertensive patients is becoming more susceptible to changes in mean arterial blood pressure. The mean arterial pressure must be higher in order to maintain the cerebral tissue perfusion constant. In the light of this information, we also aim to investigate the hemodynamic changes that may occur during anaesthesia induction, the cerebral tissue oxygen saturation in hypertensive patients and hence the effect on cerebral tissue perfusion.
Interventions
The patients ' demographic data will be recorded. 200 patients who will undergo general anaesthesia will be included in the study. Patients will be allocated to two groups with and without hypertension. Patients will be taken to the operating room after they receive their consents and demographic information. As a standard, noninvasive blood pressure, SpO2 and ECG will be monitored. Cerebral oxygenation will be monitored with near-infrared spectroscopy pallets placed on patients' foreheads. Stan
The patients ' demographic data will be recorded. 200 patients who will undergo general anaesthesia will be included in the study. Patients will be allocated to two groups with and without hypertension. Patients will be taken to the operating room after they receive their consents and demographic information. As a standard, noninvasive blood pressure, SpO2 and ECG will be monitored. Cerebral oxygenation will be monitored with near-infrared spectroscopy pallets placed on patients' foreheads. Standard general anaesthesia induction will be performed by the patient's anesthesiologist. Heart rate, blood pressure, SpO2, endtidal CO2, and cerebral oxygen saturation will be recorded by the investigator at pre-induction, post-induction, post-intubation and until surgical initiation with intervals of 5 minutes. Patients with hypertension; the duration of the hypertension, the antihypertensive medication used, and the last taken time information received. General anaesthetic drugs applied to the patient will be recorded. Follow-up of the patient will be terminated after initiation of surgery.
Sponsors
YASIN TASKALDIRAN
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
over 18 years ASA I-III Those who undergo general anesthesia
Exclusion criteria
Under 18 years old ASA IV-VI Emergency Patients Hemodynamically unstable patients Pregnant women Those with cerebrovascular disease Cranial Surgery Carotid stenosis and carotid operation
Outcome results
None listed