None listed
Conditions
Brief summary
Background: Preeclampsia is a pregnancy complication, associated with fetal, and maternal morbidity. There is no established test that fulfills all criteria as a good predictor of preeclmpsia. Objectives: This prospective comparative study designed to evaluate the accuracy of calcium-creatinine ratio (CCR) in spot urine sample in prediction of preeclampsia. Study Design: Prospective comparative study. Patient and methods: The study will include women between 20-40 years old, attending the ante-natal clinic of Ahmadi hospital for ante-natal care during the period from May 2018 till May 2019 after informed consent, and approval of the Obstetrics department . After complete obstetrical history, clinical examination, the necessary investigations will be done to exclude other conditions affecting urinary calcium/creatinine ratio. As part of the routine follow-up in the ante-natal clinics, the urine sample taken from the pregnant women for urine albumin assessment, will be used for the assessment of the CCR after informed consent. Follow–up of the studied women till delivery; women who will develop preeclampsia will constitute the study group, and other normotensive women without preeclampsia will constitute the controls.
Interventions
As part of the routine follow-up in the ante-natal clinics, the urine sample taken from the pregnant women for urine albumin assessment at 12 weeks` and 30 weeks` gestation, and will be used for the assessment of the calcium-creatinine ratio after informed consent.
Sponsors
Department of Obstetrics and Gynecology, Ahmadi hospital, Kuwait.
Eligibility
Sex/Gender
All
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
The study will include women between 20-40 years old, attending the ante-natal clinic of for ante-natal care during the period from May 2018 till May 2020 after informed consent, and approval of the Obstetrics department . Women <20 years, >40 years age, refused to participate in the study and/or refused to give consent will excluded from the study. A complete obstetrical history, clinical examination, the necessary investigations will be done to exclude other conditions affecting urinary calcium/creatinine ratio. As part of the routine follow-up in the ante-natal clinics, the urine sample taken from the pregnant women for urine albumin assessment, will be used for the assessment of the calcium-creatinine ratio after informed consent. Follow–up of the studied women till delivery; women who will develop preeclampsia will constitute the study group, and other normotensive women without preeclampsia will constitute the controls.
Exclusion criteria
Women <20 years, >40 years age, refused to participate in the study and/or refused to give consent will excluded from the study.
Outcome results
None listed